INT5643

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Context Info
Confidence 0.35
First Reported 1989
Last Reported 2007
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.94
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SERPINF2) extracellular region (SERPINF2)
Anatomy Link Frequency
neutrophil 1
SERPINF2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 10 100.00 Very High Very High Very High
tetrodotoxin 1 98.52 Very High Very High Very High
headache 1 74.08 Quite High
agonist 1 69.48 Quite High
Neurotransmitter 1 63.60 Quite High
Disease Link Frequency Relevance Heat
Hepatotoxicity 1 94.60 High High
Natriuresis 1 87.60 High High
Anaphylaxis 1 80.00 Quite High
Bacteremia 1 78.96 Quite High
Colon Cancer 1 77.96 Quite High
Shock 2 76.36 Quite High
Fever 1 75.20 Quite High
Vomiting 2 74.92 Quite High
Headache 1 74.08 Quite High
Chills 1 73.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The AAP activating enzymes were active for at least 21 days and their activity was maintained during at least four repeated cycles of exposure to AAP.
Positive_regulation (active) of AAP associated with paracetamol
1) Confidence 0.35 Published 2007 Journal ALTEX Section Abstract Doc Link 17361319 Disease Relevance 0.09 Pain Relevance 0.86
Human neutrophil elastase complexed to alpha 1-antitrypsin was increased in the patient's plasma, while the levels of the complexes thrombin-antithrombinIII and plasmin-alpha 2-antiplasmin, indicating recent coagulation or fibrinolysis, respectively, were not elevated.
Neg (not) Positive_regulation (elevated) of plasmin-alpha 2-antiplasmin in neutrophil
2) Confidence 0.32 Published 1989 Journal Toxicology Section Abstract Doc Link 2469140 Disease Relevance 0.68 Pain Relevance 0.07
The AP II-provoked increase in PD was blocked by the neurotoxin tetrodotoxin.
Positive_regulation (increase) of AP II associated with tetrodotoxin
3) Confidence 0.00 Published 1992 Journal Gastroenterology Section Abstract Doc Link 1312972 Disease Relevance 0.17 Pain Relevance 0.17

General Comments

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