INT56491

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Context Info
Confidence 0.12
First Reported 1993
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 3.38
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tnfrsf8) molecular_function (Tnfrsf8) cellular_component (Tnfrsf8)
Anatomy Link Frequency
T-cell 2
macrophages 1
Tnfrsf8 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
spinal stenosis 1 80.48 Quite High
imagery 1 76.92 Quite High
Inflammation 7 75.00 Quite High
headache 1 74.20 Quite High
Pain 3 74.04 Quite High
Neuritis 1 73.32 Quite High
Spinal cord 2 70.32 Quite High
fibrosis 1 67.04 Quite High
backache 3 59.36 Quite High
Inflammatory marker 2 54.12 Quite High
Disease Link Frequency Relevance Heat
Lymphatic System Cancer 30 98.24 Very High Very High Very High
Cancer 3 90.64 High High
Mycobacterial Infection 4 87.68 High High
Disease 24 87.44 High High
Diffuse Large B-cell Lymphoma 1 87.44 High High
Empyema Thoracis 5 84.52 Quite High
Spinal Tuberculosis 1 84.00 Quite High
Lymphadenopathy 3 81.84 Quite High
Spinal Stenosis 1 80.48 Quite High
Pneumothorax 1 78.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cells within the specimen were positive for CD30 and CD20 (Figure 6).
Positive_regulation (positive) of CD30
1) Confidence 0.12 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2311296 Disease Relevance 1.04 Pain Relevance 0.16
Surface antigen expression was further investigated in cultured cells, showing that the cultured cells did not express representative B-cell markers, except for CD20, as well as T-cell markers, but were positive for CD16, CD30, and CD103.
Neg (not) Positive_regulation (positive) of CD30 in T-cell
2) Confidence 0.03 Published 2005 Journal Virchows Arch. Section Abstract Doc Link 16021507 Disease Relevance 1.24 Pain Relevance 0.07
Some of the macrophages were also activated (CD4+/CD11c+/CD25+/CD30-).
Positive_regulation (activated) of CD30 in macrophages
3) Confidence 0.02 Published 1993 Journal J. Submicrosc. Cytol. Pathol. Section Abstract Doc Link 8096431 Disease Relevance 0.89 Pain Relevance 0.24
Immunoperoxidase stains performed on the cell block/core specimen showed that the large atypical cells were positive for CD2, CD30, CD43 and CD56, TIA-1, granzyme, and perforin, but for none of the other T-cell markers used (CD3, CD4, CD5, CD8, CD45RO), which stained the abundant background lymphocytes.
Positive_regulation (positive) of CD30 in T-cell
4) Confidence 0.01 Published 2009 Journal Diagn. Cytopathol. Section Abstract Doc Link 19373919 Disease Relevance 0.21 Pain Relevance 0.11

General Comments

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