INT5650

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.77
First Reported 1982
Last Reported 2011
Negated 0
Speculated 3
Reported most in Abstract
Documents 117
Total Number 120
Disease Relevance 80.27
Pain Relevance 26.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mpo) extracellular space (Mpo) aging (Mpo)
Anatomy Link Frequency
neutrophil 18
plasma 13
liver 6
PGE2 5
blood 4
Mpo (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 44 100.00 Very High Very High Very High
chemokine 40 100.00 Very High Very High Very High
Morphine 43 99.98 Very High Very High Very High
Hyperalgesia 18 99.96 Very High Very High Very High
Thermal hyperalgesia 2 99.96 Very High Very High Very High
Angina 46 99.88 Very High Very High Very High
Central grey 21 99.88 Very High Very High Very High
cINOD 101 99.78 Very High Very High Very High
vincristine 36 99.66 Very High Very High Very High
Acupuncture 336 99.30 Very High Very High Very High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 699 100.00 Very High Very High Very High
Myocardial Infarction 82 100.00 Very High Very High Very High
Cancer 38 100.00 Very High Very High Very High
Necrosis 37 100.00 Very High Very High Very High
Pressure And Volume Under Development 27 100.00 Very High Very High Very High
Shock 11 100.00 Very High Very High Very High
Bacterial Respiratory Disease 1 100.00 Very High Very High Very High
Hyperalgesia 23 99.96 Very High Very High Very High
Pulmonary Disease 123 99.88 Very High Very High Very High
Angina 19 99.88 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Four hours after NSAIDs, the following parameters were assessed: histomorphometric evaluation of gastric mucosal damage; gastric mucosal levels of myeloperoxidase (MPO), malondialdehyde (MDA), reduced glutathione as an index of non-proteic sulfhydryl compounds (GSH), and prostaglandin E2 (PGE2); mucosal cyclooxygenase-1 and -2 (COX-1, COX-2) mRNA expression by reverse transcription-polymerase chain reaction (RT-PCR).
Gene_expression (levels) of MPO in PGE2 associated with cinod and urological neuroanatomy
1) Confidence 0.77 Published 2005 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 16080005 Disease Relevance 0.25 Pain Relevance 0.67
Four hours after NSAIDs, the following parameters were assessed: histomorphometric evaluation of gastric mucosal damage; gastric mucosal levels of myeloperoxidase (MPO), malondialdehyde (MDA), reduced glutathione as an index of non-proteic sulfhydryl compounds (GSH), and prostaglandin E2 (PGE2); mucosal cyclooxygenase-1 and -2 (COX-1, COX-2) mRNA expression by reverse transcription-polymerase chain reaction (RT-PCR).
Gene_expression (levels) of myeloperoxidase in PGE2 associated with cinod and urological neuroanatomy
2) Confidence 0.77 Published 2005 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 16080005 Disease Relevance 0.25 Pain Relevance 0.67
Morphine produced a significant decrease in carrageenan-induced hindpaw swelling and MPO in both strains, but morphine did not significantly alter circulating cytokine/mediator levels.
Gene_expression (produced) of MPO associated with pressure and volume under development, urological neuroanatomy, sprains and strains, cytokine and morphine
3) Confidence 0.77 Published 2007 Journal Brain Behav. Immun. Section Abstract Doc Link 16603335 Disease Relevance 1.30 Pain Relevance 1.63
Myeloperoxidase activity was expressed as change in optical density/min/g/l protein.

6-Keto-prostaglandin F1?

Gene_expression (expressed) of Myeloperoxidase
4) Confidence 0.76 Published 2000 Journal Crit Care Section Body Doc Link PMC29035 Disease Relevance 0 Pain Relevance 0
BACKGROUND: Myeloperoxidase (MPO) is a highly expressed enzyme due to leukocyte activation, with multiple atherogenic actions, including LDL cholesterol oxidation, and is related to the instability of atherosclerotic plaque.
Gene_expression (expressed) of Myeloperoxidase in plaque associated with atherosclerotic plaque and urological neuroanatomy
5) Confidence 0.75 Published 2007 Journal Arq. Bras. Cardiol. Section Abstract Doc Link 18317620 Disease Relevance 0.27 Pain Relevance 0.15
BACKGROUND: Myeloperoxidase (MPO) is a highly expressed enzyme due to leukocyte activation, with multiple atherogenic actions, including LDL cholesterol oxidation, and is related to the instability of atherosclerotic plaque.
Gene_expression (expressed) of MPO in plaque associated with atherosclerotic plaque and urological neuroanatomy
6) Confidence 0.75 Published 2007 Journal Arq. Bras. Cardiol. Section Abstract Doc Link 18317620 Disease Relevance 0.27 Pain Relevance 0.15
Myeloperoxidase (MPO), a heme protein abundantly expressed and secreted by polymorphonuclear neutrophils (PMN), has emerged as a critical mediator in coronary atherosclerosis.
Gene_expression (expressed) of Myeloperoxidase in PMN associated with coronary artery disease and urological neuroanatomy
7) Confidence 0.72 Published 2009 Journal Free Radic. Biol. Med. Section Abstract Doc Link 19362143 Disease Relevance 0.83 Pain Relevance 0
Myeloperoxidase (MPO), a heme protein abundantly expressed and secreted by polymorphonuclear neutrophils (PMN), has emerged as a critical mediator in coronary atherosclerosis.
Gene_expression (expressed) of MPO in PMN associated with coronary artery disease and urological neuroanatomy
8) Confidence 0.72 Published 2009 Journal Free Radic. Biol. Med. Section Abstract Doc Link 19362143 Disease Relevance 0.83 Pain Relevance 0
Plasma levels of 3-Cl-Tyr, a product of MPO, were analyzed by HPLC coupled with Coularray electrochemical detection.
Gene_expression (product) of MPO in Plasma
9) Confidence 0.69 Published 2008 Journal Clin. Biochem. Section Body Doc Link 18314009 Disease Relevance 0.17 Pain Relevance 0
Determination of Myeloperoxidase (MPO) Activity
Gene_expression (Determination) of Myeloperoxidase associated with urological neuroanatomy
10) Confidence 0.68 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2804053 Disease Relevance 0.25 Pain Relevance 0.03
Determination of Myeloperoxidase (MPO) Activity
Gene_expression (Determination) of MPO associated with urological neuroanatomy
11) Confidence 0.68 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2804053 Disease Relevance 0.25 Pain Relevance 0.03
MPO activity was expressed as U per g tissue.
Gene_expression (expressed) of MPO associated with urological neuroanatomy
12) Confidence 0.67 Published 2010 Journal J Brachial Plex Peripher Nerve Inj Section Body Doc Link PMC2890670 Disease Relevance 0.44 Pain Relevance 0.14
Estimation of myeloperoxidase activity
Gene_expression (activity) of myeloperoxidase
13) Confidence 0.67 Published 2010 Journal J Brachial Plex Peripher Nerve Inj Section Body Doc Link PMC2890670 Disease Relevance 0.19 Pain Relevance 0.13
Pulmonary myeloperoxidase activity
Gene_expression (activity) of myeloperoxidase
14) Confidence 0.66 Published 2000 Journal Crit Care Section Body Doc Link PMC29035 Disease Relevance 0.07 Pain Relevance 0.07
PURPOSE: To determine whether anti neutrophil cytoplasmic antibodies (ANCA): anti myeloperoxidase (anti MPO) and anti proteinase 3 (anti PR3), are present in patients with sickle cell anaemia (SCA) during painful crisis.
Gene_expression (present) of anti myeloperoxidase in neutrophil associated with sickle cell anemia, pain and urological neuroanatomy
15) Confidence 0.66 Published 1999 Journal Sangre (Barc) Section Abstract Doc Link 10618917 Disease Relevance 0.27 Pain Relevance 0.10
I/R significantly increased NADPH oxidase activity, H(2)O(2) production, and myeloperoxidase (MPO) activity.
Gene_expression (production) of MPO associated with urological neuroanatomy
16) Confidence 0.65 Published 2009 Journal J. Pharmacol. Sci. Section Abstract Doc Link 19942802 Disease Relevance 0.46 Pain Relevance 0.26
I/R significantly increased NADPH oxidase activity, H(2)O(2) production, and myeloperoxidase (MPO) activity.
Gene_expression (production) of myeloperoxidase associated with urological neuroanatomy
17) Confidence 0.65 Published 2009 Journal J. Pharmacol. Sci. Section Abstract Doc Link 19942802 Disease Relevance 0.46 Pain Relevance 0.26
However, most NSAIDs were more effective against MPO-CL.
Gene_expression (effective) of MPO associated with cinod and urological neuroanatomy
18) Confidence 0.65 Published 1982 Journal Agents Actions Section Abstract Doc Link 6282074 Disease Relevance 1.52 Pain Relevance 1.14
Endpoints at 4, 6, and 10 h were serum amylase, myeloperoxidase activity (MPO), and spinal cord Fos expression (number of immunoreactive nuclei/section dorsal gray matter).
Gene_expression (expression) of myeloperoxidase in gray matter associated with urological neuroanatomy and spinal cord
19) Confidence 0.65 Published 2004 Journal J. Surg. Res. Section Abstract Doc Link 15047123 Disease Relevance 0.66 Pain Relevance 0.38
E to TL ratio and myeloperoxidase (MPO) were studied in 20 patients undergoing lumbar spinal surgery and randomly allocated to two anesthetic groups: propofol (bolus dose + continuous infusion and thiopental/isoflurane.
Gene_expression (studied) of MPO in spinal associated with urological neuroanatomy and isoflurane
20) Confidence 0.64 Published 1991 Journal Acta Anaesthesiol Scand Section Abstract Doc Link 1649539 Disease Relevance 0.16 Pain Relevance 0.24

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox