INT56695

Context Info Confidence 0.25 First Reported 1993 Last Reported 1993 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.35

plasma membrane (Antxr1)

Anatomy Link Frequency cerebral cortex 2 Antxr1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat noradrenaline 2 98.04 cerebral cortex 2 96.04 tetrodotoxin 1 85.36 antagonist 1 69.04 Glutamate 1 57.92 nMDA receptor 1 53.04

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Toxin I, a K+ channel blocker found in the venom of the black mamba snake with close sequence homology to the dendrotoxins, produced a concentration-related enhancement of both spontaneous and electrically evoked [3H]noradrenaline ([3H]NA) release from slices of rat cerebral cortex.

Positive_regulation (enhancement) of Gene_expression (produced) of Toxin I in cerebral cortex associated with noradrenaline and cerebral cortex

1) Confidence 0.25 Published 1993 Journal Eur. J. Pharmacol. Section Abstract Doc Link 8101819 Disease Relevance 0 Pain Relevance 0.35

General Comments

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