INT5680
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
A substantial increase in NGF protein expression occurred in skin 4-h, 1-day and 2-days and 5-days after incision comparing contralateral uninjured skin. | |||||||||||||||
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This suggests that expression of capsaicin sensitivity in DRG is maximal at levels of NGF found in normal animals. | |||||||||||||||
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We also analyzed changes in the expression of nerve growth factor (NGF), which is involved in plasticity of the nociceptive circuit after nerve injury. | |||||||||||||||
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We also analyzed changes in the expression of nerve growth factor (NGF), which is involved in plasticity of the nociceptive circuit after nerve injury. | |||||||||||||||
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Therapeutic strategies targeting spinal cord cells that produce NGF may prevent primary afferent sprouting and resulting clinical disorders after cord injury. | |||||||||||||||
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The skin immediately adjacent to the incision had the greatest NGF expression. | |||||||||||||||
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The purpose of this study is to examine the expression of NGF in skin after planter incision. | |||||||||||||||
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NGF protein expression was detected by Western blot and immunohistochemistry in incisions. | |||||||||||||||
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CONCLUSION: NGF mRNA is increased and a large-molecular-weight form of NGF protein is expressed in the region adjacent to the incision. | |||||||||||||||
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At 3-7 days after transection or clip-compression SCI, NGF mRNA and protein were expressed in the lesion and throughout the intermediate grey matter and white matter rostral and caudal to the injury site. | |||||||||||||||
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Rounded macrophages in the lesion were immunoreactive (Ir) for NGF, but the cells expressing NGF mRNA were not in the same areas of the lesion and were not stained by a macrophage marker. | |||||||||||||||
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Nerve growth factor expression is up-regulated in the rat model of L-arginine-induced acute pancreatitis. | |||||||||||||||
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The NGF-induced recovery of noradrenergic nerves was independent of the presence of sensory peptidergic afferents and it could not be mimicked by a local inflammatory response known to raise endogenous NGF production. | |||||||||||||||
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Prior studies have demonstrated an association between visceral inflammation, an increase in nerve growth factor (NGF) expression, and development of hyperalgesia. | |||||||||||||||
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These data demonstrate that a transient increase in NGF expression without associated inflammation sensitizes visceral reflex pathways, leading to bladder overactivity. | |||||||||||||||
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Prior studies have demonstrated an association between visceral inflammation, an increase in nerve growth factor (NGF) expression, and development of hyperalgesia. | |||||||||||||||
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Increased nerve growth factor expression triggers bladder overactivity. | |||||||||||||||
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Expression of NGF led to bladder overactivity, whereas beta-galactosidase expression was without effect. | |||||||||||||||
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We also found that NGF produced plasma extravasation in rat skin, using the Evan's blue method, with a dose dependency similar to that determined for hyperalgesia. | |||||||||||||||
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Cerebellar and striatal, but not hippocampal, astrocytes prepared from naltrexone-treated animals produced higher levels of NGF than those from controls. | |||||||||||||||
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General Comments
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