INT5681

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Context Info
Confidence 0.60
First Reported 1980
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 1.92
Pain Relevance 2.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Avpr1a) response to stress (Avpr1a) signal transducer activity (Avpr1a)
Anatomy Link Frequency
lobe 1
Avpr1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opiate 4 99.40 Very High Very High Very High
Opioid 8 98.68 Very High Very High Very High
Enkephalin 10 97.82 Very High Very High Very High
Dopamine 2 97.20 Very High Very High Very High
Morphine 3 96.96 Very High Very High Very High
Endogenous opioid 1 93.08 High High
narcan 4 81.60 Quite High
antagonist 1 78.88 Quite High
Inflammation 11 54.64 Quite High
Serotonin 1 35.04 Quite Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 7 99.38 Very High Very High Very High
Heart Rate Under Development 8 98.32 Very High Very High Very High
Oliguria 2 98.08 Very High Very High Very High
Acidosis 2 95.52 Very High Very High Very High
Asthma 86 92.48 High High
Increased Venous Pressure Under Development 3 85.48 High High
Acid Base Imbalance 6 69.56 Quite High
Bronchospasm 1 68.96 Quite High
Respiratory Failure 9 66.68 Quite High
Dyspnea 4 64.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that opioid stimulation of this structure induces an inhibitory effect on renal water, Na+ and K+ excretion, and that antidiuretic hormone release is probably not important to these phenomena.
Localization (release) of antidiuretic hormone associated with opioid
1) Confidence 0.60 Published 1992 Journal Physiol. Behav. Section Abstract Doc Link 1313588 Disease Relevance 0.08 Pain Relevance 0.49
Some investigators claimed that antidiuretic hormone release could be a mechanism explaining opioid-induced oliguria.
Localization (release) of antidiuretic hormone associated with oliguria and opioid
2) Confidence 0.60 Published 1992 Journal Physiol. Behav. Section Abstract Doc Link 1313588 Disease Relevance 0.10 Pain Relevance 0.53
These results suggest that the regulation of the enkephalin system in the anterior lobe may be mediated, at least in part, by the dopamine system, whereas the enkephalin system in the neurointermediate lobe may be regulated mainly through a mechanism similar to that regulating antidiuretic hormone release.
Localization (release) of antidiuretic hormone in lobe associated with dopamine and enkephalin
3) Confidence 0.60 Published 1983 Journal Endocrinology Section Abstract Doc Link 6311513 Disease Relevance 0 Pain Relevance 0.38
Thus administration of opiates produces a rapid increase in release of prolactin (PRL), growth hormone (GH), adrenocorticotropin (ACTH), and antidiuretic hormone (ADH), and a decrease in release of gonadotropins and thyrotropin (TSH).
Localization (release) of antidiuretic hormone associated with opiate
4) Confidence 0.19 Published 1980 Journal Fed. Proc. Section Abstract Doc Link 6247213 Disease Relevance 0.06 Pain Relevance 0.59
Fluid overload caused by overhydration during treatment or fluid retention associated with inappropriate secretion of antidiuretic hormone, will put the patient further at risk of pulmonary oedema [21,22].
Localization (secretion) of antidiuretic hormone associated with heart rate under development and pressure and volume under development
5) Confidence 0.09 Published 2009 Journal Scand J Trauma Resusc Emerg Med Section Body Doc Link PMC2749010 Disease Relevance 1.68 Pain Relevance 0.03

General Comments

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