INT56955

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Context Info
Confidence 0.27
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 2.92
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MYOG) nucleus (MYOG) DNA binding (MYOG)
Anatomy Link Frequency
smooth muscle 2
MYOG (Homo sapiens)
Pain Link Frequency Relevance Heat
tetrodotoxin 5 97.12 Very High Very High Very High
Kinase C 5 92.00 High High
Action potential 1 64.40 Quite High
Spinal cord 3 62.24 Quite High
imagery 4 10.28 Low Low
Pain 3 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alveolar Rhabdomyosarcoma 3 99.64 Very High Very High Very High
Cancer 74 97.00 Very High Very High Very High
Primitive Neuroectodermal Tumors 27 96.72 Very High Very High Very High
Necrosis 4 93.96 High High
Malignant Neoplastic Disease 6 92.52 High High
Sarcoma 59 86.80 High High
Bone Cancer 9 84.80 Quite High
Rhinitis 3 79.32 Quite High
Multiple Myeloma 1 76.20 Quite High
Hyperplasia 2 73.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Collectively, the data suggest that the regulation of MHC isoform expression involves a complex interaction of multiple control mechanisms including the myogenin:MyoD and calcineurin:NF-AT pathways; however, other intracellular signaling pathways are likely to contribute.
myogenin Binding (interaction) of
1) Confidence 0.27 Published 2000 Journal Muscle Nerve Section Abstract Doc Link 10797389 Disease Relevance 0.11 Pain Relevance 0.18
Recombinant chick myogenin binds to myogenic sites (E boxes) present in the AChR alpha-subunit promoter but loses this binding capacity after phosphorylation.
myogenin Binding (binds) of
2) Confidence 0.23 Published 1994 Journal Biochemistry Section Abstract Doc Link 8117718 Disease Relevance 0 Pain Relevance 0.55
The spindle cells were found to be positive for vimentin and smooth muscle actin and negative for desmin, S-100 protein, myogenin and CD68 on immunohistochemistry.
myogenin Binding (negative) of in smooth muscle
3) Confidence 0.17 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2873452 Disease Relevance 0.69 Pain Relevance 0
Alveolar rhabdomyosarcoma was ruled out by negative myogenin and myoD1 and by absence of PAX3/PAX7-FKHR translocations by FISH.
myogenin Binding (negative) of associated with alveolar rhabdomyosarcoma
4) Confidence 0.06 Published 2010 Journal Mol Cytogenet Section Body Doc Link PMC2908072 Disease Relevance 1.09 Pain Relevance 0
On the other hand, she was negative for cytokeratin, epithelial membrane antigen, desmin, Myo D-1, myogenin and smooth muscle actin.
myogenin Binding (cytokeratin) of in smooth muscle
5) Confidence 0.02 Published 2010 Journal J Med Case Reports Section Abstract Doc Link PMC2848680 Disease Relevance 1.03 Pain Relevance 0

General Comments

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