INT57000

Context Info Confidence 0.78 First Reported 1994 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 21 Total Number 22 Disease Relevance 11.01 Pain Relevance 10.01

lipid binding (LBP) transport (LBP) extracellular space (LBP) extracellular region (LBP)

Anatomy Link Frequency leg 3 joint 1 body 1 placenta 1 LBP (Homo sapiens)

Pain Link Frequency Relevance Heat backache 587 100.00 Chronic low back pain 29 100.00 Pain 84 98.84 imagery 15 98.84 withdrawal 1 88.24 Lasting pain 4 80.24 depression 12 50.00 Analgesic 4 50.00 Arthritis 3 5.00 Pain score 2 5.00

Disease Link Frequency Relevance Heat Low Back Pain 624 100.00 Nicotine Addiction 173 99.68 Cancer 2 99.00 Pain 82 98.84 Back Injuries 53 94.80 Injury 29 92.76 Intervertebral Disk Degeneration 3 80.72 Phobia 1 58.48 Depression 27 50.00 Arthralgia 1 50.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These results suggest that localized LBP intensity and radiating leg pain may represent two different approaches in assessing back pain severity.

Localization (localized) of LBP in leg associated with pain, chronic low back pain and backache

1) Confidence 0.78 Published 1999 Journal J Clin Epidemiol Section Abstract Doc Link 10527000 Disease Relevance 1.20 Pain Relevance 1.49

Localized LBP however, did not predict long-term work disability, while LBP accompanied by widespread pain did (OR = 3.52, 95% CI = 1.09-11.37), also after adjustments for demographic, lifestyle, and work-related factors.

Localization (Localized) of LBP

2) Confidence 0.78 Published 2002 Journal Scand J Public Health Section Body Doc Link 12680505 Disease Relevance 0 Pain Relevance 0

CONCLUSION: LBP in persons with widespread musculoskeletal pain predicted long-term work disability, while localized LBP did not.

Localization (localized) of LBP

3) Confidence 0.78 Published 2002 Journal Scand J Public Health Section Body Doc Link 12680505 Disease Relevance 0 Pain Relevance 0

A body diagram was used to explicitly identify the location of LBP in the SHBPS [3].

Localization (location) of LBP in body associated with backache

4) Confidence 0.75 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2277439 Disease Relevance 1.27 Pain Relevance 0.86

It is therefore unlikely that awkward occupational postures are independently causative of LBP in the populations of workers studied.

Localization (causative) of LBP

5) Confidence 0.73 Published 2010 Journal Spine J Section Body Doc Link 19910263 Disease Relevance 0 Pain Relevance 0

From 273 predominantly male army workers (mean age 39 +/- 10.5 years, range 20-56 years, 4 women) with LBP who were recruited in three randomized clinical trials, baseline individual patient factors, pain-related factors, work-related psychosocial factors, and psychological factors were evaluated as potential prognostic variables in a short-term (post-treatment) and a long-term logistic regression model (6 months after treatment).

Localization (recruited) of LBP associated with pain and backache

6) Confidence 0.73 Published 2010 Journal Eur Spine J Section Abstract Doc Link 20035358 Disease Relevance 0.52 Pain Relevance 0.46

Based on the evidence reviewed, it is unlikely that occupational standing or walking is independently causative of LBP in the populations of workers studied.

Localization (causative) of LBP

7) Confidence 0.73 Published 2010 Journal Spine J Section Body Doc Link 20207335 Disease Relevance 0 Pain Relevance 0

The current study supports the findings of other studies that introducing transfer technique alone has no effect in targeting LBP.

Localization (targeting) of LBP associated with backache

8) Confidence 0.73 Published 2008 Journal Ergonomics Section Abstract Doc Link 18803093 Disease Relevance 0.49 Pain Relevance 0.81

Based on the evidence reviewed, it is unlikely that occupational pushing or pulling is independently causative of LBP in the populations of workers studied.

Neg (independently) Localization (causative) of LBP

9) Confidence 0.73 Published 2010 Journal Spine J Section Body Doc Link 20494815 Disease Relevance 0 Pain Relevance 0

The use of opioids by patients with LBP represents a major cost for the health plan, and is associated with specific patient characteristics and their use of other LBP services.

Localization (use) of LBP

10) Confidence 0.73 Published 2005 Journal Spine Section Body Doc Link 15864162 Disease Relevance 0 Pain Relevance 0

Over the same time, the U.S. rate of nonsurgical LBP hospitalization declined, as did average lengths of stay for both types of LBP hospitalization.

Localization (hospitalization) of LBP

11) Confidence 0.73 Published 1994 Journal Clin J Pain Section Body Doc Link 8193446 Disease Relevance 0 Pain Relevance 0

Based on these results, it is unlikely that occupational sitting is independently causative of LBP in the populations of workers studied.

Localization (causative) of LBP

12) Confidence 0.73 Published 2010 Journal Spine J Section Body Doc Link 20097618 Disease Relevance 0 Pain Relevance 0

However, several theories may explain why smokers might be prone to increased rates of LBP.

Localization (rates) of LBP associated with nicotine addiction and backache

13) Confidence 0.71 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004651 Disease Relevance 1.81 Pain Relevance 0.82

The frequency of LBP is presented in table 2.

Localization (presented) of LBP associated with backache

14) Confidence 0.70 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2967511 Disease Relevance 1.22 Pain Relevance 1.22

Smoking status and the presence of LBP were assessed in the subjects, and information about possible confounders was also obtained.

Localization (presence) of LBP associated with nicotine addiction and backache

15) Confidence 0.70 Published 2010 Journal Journal of pain research Section Body Doc Link PMC3004651 Disease Relevance 0.64 Pain Relevance 0.21

Those that reached the highest levels of consensus were a positive response to facet joint injection, localized unilateral LBP, positive medial branch block, pain upon unilateral palpation of the LZJ or transverse process, lack of radicular features, pain eased by flexion, and pain, if referred, located above the knee.

Localization (localized) of LBP in joint

16) Confidence 0.68 Published 2007 Journal Phys Ther Section Body Doc Link 17684091 Disease Relevance 0.08 Pain Relevance 0

RESULTS: After adjustment for individual and physical risks, including occasional back pain at baseline, the prevalence rate of LBP in men is significantly related to baseline low decision latitude and low social support at work, and nonsignificantly to high job strain, low wage and job satisfaction, feeling stressed at work, and feeling depressed.

Localization (rate) of LBP

17) Confidence 0.68 Published 2007 Journal Spine Section Body Doc Link 17224824 Disease Relevance 0 Pain Relevance 0

Using analysis of variance and multiple regression analysis, we compared the relative importance of localized LBP intensity and radiating leg pain in explaining the variability in the means of the SF-36 scales and low back disability days, and in the proportion of patients who had used diagnostic imaging.

Localization (localized) of LBP in leg associated with pain, chronic low back pain and imagery

18) Confidence 0.68 Published 1999 Journal J Clin Epidemiol Section Abstract Doc Link 10527000 Disease Relevance 1.20 Pain Relevance 1.36

The results of the study indicate that measures of localized LBP intensity and radiating leg pain contribute separately to the assessment of patient functional status, low back disability, and use of diagnostic imaging.

Localization (localized) of LBP in leg associated with pain, chronic low back pain and imagery

19) Confidence 0.68 Published 1999 Journal J Clin Epidemiol Section Abstract Doc Link 10527000 Disease Relevance 1.22 Pain Relevance 1.49

A tendency was observed between posterior/fundal location of the placenta to the presence of LBP during pregnancy.

Localization (presence) of LBP in placenta

20) Confidence 0.68 Published 1994 Journal Acta Obstet Gynecol Scand Section Body Doc Link 8122500 Disease Relevance 0.07 Pain Relevance 0

General Comments

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