INT57029

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Context Info
Confidence 0.40
First Reported 1994
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 4.52
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (HEXB) cell death (HEXB) carbohydrate metabolic process (HEXB)
lysosome (HEXB)
Anatomy Link Frequency
monocytes 1
neuron 1
uterine 1
HEXB (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 1 95.40 Very High Very High Very High
Pain 1 93.28 High High
backache 1 92.80 High High
headache 1 91.48 High High
methotrexate 5 88.64 High High
abdominal pain 2 83.28 Quite High
spinal inflammation 2 50.00 Quite Low
Inflammation 1 50.00 Quite Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 7 99.54 Very High Very High Very High
Lymphatic System Cancer 1 99.32 Very High Very High Very High
Pleural Effusion 1 99.12 Very High Very High Very High
Disease 2 98.24 Very High Very High Very High
Metastasis 5 98.20 Very High Very High Very High
Hydatidiform Mole 1 95.20 Very High Very High Very High
Reprotox - General 2 14 95.08 Very High Very High Very High
Low Back Pain 3 92.80 High High
Headache 1 91.48 High High
Embryonal Carcinoma 2 90.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum beta subunit of human chorionic gonadotropin was abnormally elevated for age of gestation.
Positive_regulation (elevated) of beta subunit
1) Confidence 0.40 Published 2006 Journal Int. J. Gynecol. Cancer Section Abstract Doc Link 16681776 Disease Relevance 0.80 Pain Relevance 0.09
Diagnostic uterine curettage may be appropriate in patients who are hemodynamically stable and whose beta subunit of human chorionic gonadotropin levels are not increasing as expected.
Neg (not) Positive_regulation (increasing) of beta subunit in uterine
2) Confidence 0.11 Published 2005 Journal Am Fam Physician Section Abstract Doc Link 16300032 Disease Relevance 0.91 Pain Relevance 0.12
If a patient has a beta subunit of human chorionic gonadotropin level of 1,500 mIU per mL or greater, but the transvaginal ultrasonography does not show an intrauterine gestational sac, ectopic pregnancy should be suspected.
Positive_regulation (has) of beta subunit associated with reprotox - general 2
3) Confidence 0.11 Published 2005 Journal Am Fam Physician Section Abstract Doc Link 16300032 Disease Relevance 0.91 Pain Relevance 0.11
RESULTS: Two-dimensional gel electrophoresis showed upregulation of proteasomal constituents in AS monocytes, including the beta subunit of proteasome activator (PA)28.
Positive_regulation (upregulation) of beta subunit in monocytes
4) Confidence 0.08 Published 2009 Journal Ann. Rheum. Dis. Section Body Doc Link 18952638 Disease Relevance 0.24 Pain Relevance 0
The serum AFP, beta-subunit of human chorionic gonadotropin (hCG-beta), CEA and CA-19-9 were elevated.
Positive_regulation (elevated) of beta-subunit
5) Confidence 0.04 Published 1994 Journal Jpn. J. Clin. Oncol. Section Abstract Doc Link 8126921 Disease Relevance 1.03 Pain Relevance 0.09
Tumor markers including lactate dehydrogenase (LDH), cancer antigen-125 (CA-125), beta-subunit of human chorionic gonadotropin (beta-hCG) and neuron-specific enolase (NSE) were elevated.
Positive_regulation (elevated) of beta-subunit in neuron associated with cancer
6) Confidence 0.03 Published 2004 Journal J. Pediatr. Surg. Section Abstract Doc Link 15359410 Disease Relevance 0.62 Pain Relevance 0.14

General Comments

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