INT57124

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.19
First Reported 1994
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.94
Pain Relevance 1.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein transporter activity (AP1B1) cytosol (AP1B1) Golgi apparatus (AP1B1)
Anatomy Link Frequency
plasma 2
adrenal medulla 1
AP1B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
medulla 5 100.00 Very High Very High Very High
opioid receptor 1 100.00 Very High Very High Very High
narcan 3 99.16 Very High Very High Very High
Calcitonin gene-related peptide 6 98.08 Very High Very High Very High
Opioid 10 97.04 Very High Very High Very High
agonist 5 95.76 Very High Very High Very High
Pain 2 91.20 High High
Kinase C 1 86.16 High High
Bile 2 85.96 High High
Neuropeptide 20 82.64 Quite High
Disease Link Frequency Relevance Heat
Nociception 2 96.80 Very High Very High Very High
Gallstones 8 92.56 High High
Pain 2 91.20 High High
Injury 2 82.56 Quite High
Anaphylaxis 1 63.04 Quite High
Disease 9 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Cardiovascular Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of BAM22, also known to activate opioid receptors, was further enhanced by combination with naloxone that had no effect on its own.
Positive_regulation (enhanced) of BAM22 associated with narcan and opioid receptor
1) Confidence 0.19 Published 2008 Journal Neuroscience Section Abstract Doc Link 18065157 Disease Relevance 0.06 Pain Relevance 0.69
The increase in plasma BAM-22P levels may contribute substantially to the increase in total circulating opioid activity documented in cholestatic rats.
Positive_regulation (increase) of BAM-22P in plasma associated with opioid
2) Confidence 0.05 Published 1994 Journal Am. J. Physiol. Section Abstract Doc Link 8141292 Disease Relevance 0.26 Pain Relevance 0.29
SNSRs are activated by proenkephalin A peptide fragments, like bovine adrenal medulla peptide 22 (BAM22).
Positive_regulation (activated) of BAM22 in adrenal medulla associated with medulla
3) Confidence 0.05 Published 2005 Journal BMC Genomics Section Body Doc Link PMC1192796 Disease Relevance 0.33 Pain Relevance 0.32
This increase in plasma BAM-22P levels was completely prevented by adrenalectomy.
Positive_regulation (increase) of BAM-22P in plasma
4) Confidence 0.04 Published 1994 Journal Am. J. Physiol. Section Abstract Doc Link 8141292 Disease Relevance 0.29 Pain Relevance 0.42

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox