INT57125

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.18
First Reported 1994
Last Reported 2007
Negated 0
Speculated 1
Reported most in Abstract
Documents 8
Total Number 10
Disease Relevance 3.80
Pain Relevance 4.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein transporter activity (AP1B1) cytosol (AP1B1) Golgi apparatus (AP1B1)
Anatomy Link Frequency
adrenal medulla 2
lamina 2
DRG 2
dorsal 1
Plasma 1
AP1B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
medulla 17 100.00 Very High Very High Very High
agonist 40 99.98 Very High Very High Very High
Inflammation 10 99.92 Very High Very High Very High
Spinal cord 20 99.68 Very High Very High Very High
dorsal root ganglion 28 99.04 Very High Very High Very High
dorsal rhizotomy 5 97.56 Very High Very High Very High
Bile 1 96.44 Very High Very High Very High
opioid receptor 62 96.32 Very High Very High Very High
Opioid 35 94.52 High High
MU agonist 3 85.12 High High
Disease Link Frequency Relevance Heat
INFLAMMATION 10 99.92 Very High Very High Very High
Ganglion Cysts 32 98.56 Very High Very High Very High
Gallstones 4 95.64 Very High Very High Very High
Injury 1 93.04 High High
Bordatella Infection 3 92.72 High High
Nociception 15 75.00 Quite High
Neuropathic Pain 5 71.44 Quite High
Pain 2 70.28 Quite High
Urological Neuroanatomy 14 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study was designed to examine the expression of BAM22 in the spinal cord and dorsal root ganglion (DRG) of naive rats as well as in a model of inflammation.
Spec (examine) Gene_expression (expression) of BAM22 in DRG associated with ganglion cysts, dorsal root ganglion, inflammation and spinal cord
1) Confidence 0.18 Published 2007 Journal Eur. J. Neurosci. Section Abstract Doc Link 17767492 Disease Relevance 0.49 Pain Relevance 0.50
BAM22-like immunoreactivity (BAM22-IR) was expressed in fibers in the spinal cord, with high density seen in lamina I in naïve rats.
Gene_expression (expressed) of BAM22 in lamina associated with spinal cord
2) Confidence 0.18 Published 2007 Journal Eur. J. Neurosci. Section Abstract Doc Link 17767492 Disease Relevance 0.51 Pain Relevance 0.54
In contrast, the deltaOR/SNSR-4 bivalent agonist BAM22, which could activate each receptor expressed individually, fully activated the SNSR-4-dependent phospholipase C but did not promote deltaOR-mediated inhibition of adenylyl cyclase in deltaOR/SNSR-4-coexpressing cells.
Gene_expression (expressed) of BAM22 associated with agonist
3) Confidence 0.16 Published 2006 Journal Mol. Pharmacol. Section Abstract Doc Link 16682504 Disease Relevance 0.07 Pain Relevance 0.43
BAM22-like immunoreactivity (BAM22-IR) was expressed in fibers in the spinal cord, with high density seen in lamina I in naïve rats.
Gene_expression (expressed) of BAM22 in lamina associated with spinal cord
4) Confidence 0.15 Published 2007 Journal Eur. J. Neurosci. Section Abstract Doc Link 17767492 Disease Relevance 0.52 Pain Relevance 0.55
The expression of BAM22-IR in the superficial laminae was greatly reduced following dorsal rhizotomy.
Gene_expression (expression) of BAM22 in dorsal associated with dorsal rhizotomy
5) Confidence 0.15 Published 2007 Journal Eur. J. Neurosci. Section Abstract Doc Link 17767492 Disease Relevance 0.52 Pain Relevance 0.55
Following injection of complete Freund's adjuvant (CFA) in the hindpaw, the expression of BAM22-IR in the superficial laminae of the spinal cord and small-sized DRG neurons on the ipsilateral side was markedly increased.
Gene_expression (expression) of BAM22 in DRG associated with dorsal root ganglion and spinal cord
6) Confidence 0.15 Published 2007 Journal Eur. J. Neurosci. Section Abstract Doc Link 17767492 Disease Relevance 0.58 Pain Relevance 0.68
In the heterologous system, the SNSR4 selective bovine adrenal medulla peptide BAM22 produces similar amounts of phospholipase C activation as it does in cells expressing only SNSR4.
Gene_expression (produces) of BAM22 in adrenal medulla associated with medulla
7) Confidence 0.08 Published 2007 Journal BMC Bioinformatics Section Body Doc Link PMC1904246 Disease Relevance 0.07 Pain Relevance 0.37
In the heterologous system, the SNSR4 selective bovine adrenal medulla peptide BAM22 produces similar amounts of phospholipase C activation as it does in cells expressing only SNSR4.
Gene_expression (selective) of BAM22 in adrenal medulla associated with medulla
8) Confidence 0.08 Published 2007 Journal BMC Bioinformatics Section Body Doc Link PMC1904246 Disease Relevance 0.07 Pain Relevance 0.43
Plasma levels of BAM-22P were determined by a sensitive radioimmunoassay, and the specificity of the assay was confirmed using high-performance liquid chromatography.
Gene_expression (levels) of BAM-22P in Plasma
9) Confidence 0.05 Published 1994 Journal Am. J. Physiol. Section Abstract Doc Link 8141292 Disease Relevance 0.26 Pain Relevance 0.47
In hippocampal neurons expressing hSNSR4, BAM8-22 induced presynaptic inhibition of transmission that was abolished after PTX treatment.
Gene_expression (expressing) of BAM8-22 in neurons
10) Confidence 0.01 Published 2004 Journal J. Neurosci. Section Abstract Doc Link 15163697 Disease Relevance 0.70 Pain Relevance 0.39

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox