INT57156

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Context Info
Confidence 0.06
First Reported 1993
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.60
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PTGER1) signal transducer activity (PTGER1)
Anatomy Link Frequency
macrophages 2
PTGER1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 5 97.24 Very High Very High Very High
cytokine 1 88.76 High High
Pain 2 86.00 High High
Inflammation 2 79.60 Quite High
Analgesic 1 68.56 Quite High
COX2 2 66.16 Quite High
tolerance 1 61.92 Quite High
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 5 97.24 Very High Very High Very High
Pain 2 86.00 High High
Arthritis 2 85.80 High High
INFLAMMATION 2 79.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In gastric mucosal incubates, acemetacin was less potent than indomethacin in causing a concentration-related inhibition of PGE accumulation (19-74% vs 34-84%; n = 6, p < 0.05).
Negative_regulation (inhibition) of Positive_regulation (accumulation) of PGE
1) Confidence 0.06 Published 1993 Journal Int J Tissue React Section Abstract Doc Link 8144313 Disease Relevance 0 Pain Relevance 0.13
This study was aimed to investigate the inhibitory mechanism of HA on lipopolysaccharide (LPS)-stimulated PGE(2) production in U937 human macrophages.
Spec (investigate) Negative_regulation (mechanism) of Positive_regulation (stimulated) of PGE in macrophages
2) Confidence 0.04 Published 2010 Journal Tohoku J. Exp. Med. Section Abstract Doc Link 20208419 Disease Relevance 0.60 Pain Relevance 0.38

General Comments

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