INT57188

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.45
First Reported 1993
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 1.89
Pain Relevance 1.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Chat) transferase activity, transferring acyl groups (Chat)
Anatomy Link Frequency
striatum 4
retina 2
lactotrophs 2
Chat (Rattus norvegicus)
Pain Link Frequency Relevance Heat
gABA 16 100.00 Very High Very High Very High
methadone 14 100.00 Very High Very High Very High
ischemia 15 99.32 Very High Very High Very High
imagery 1 78.16 Quite High
Inflammation 36 70.48 Quite High
Glutamate 34 62.32 Quite High
cerebral cortex 9 59.12 Quite High
Nicotine 11 46.48 Quite Low
Action potential 3 27.60 Quite Low
withdrawal 18 25.00 Low Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 10 99.32 Very High Very High Very High
Cirrhosis 19 96.56 Very High Very High Very High
Liver Disease 8 90.48 High High
Arteritic Anterior Ischaemic Optic Neuropathy 1 90.12 High High
Retina Disease 1 89.20 High High
Aging 1 88.88 High High
Stress 55 81.80 Quite High
Hepatic Encephalopathy 17 81.08 Quite High
Urological Neuroanatomy 7 78.88 Quite High
Frailty 1 75.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of prenatal exposure to methadone via maternal osmotic minipumps on the expression of acetylcholinesterase (AChE) and choline acetyltransferase (ChAT) has been studied by light microscopy in the striatum of male and female rats.
Regulation (effect) of Gene_expression (expression) of ChAT in striatum associated with methadone
1) Confidence 0.45 Published 1993 Journal Brain Res. Dev. Brain Res. Section Abstract Doc Link 8149590 Disease Relevance 0 Pain Relevance 0.32
The effect of prenatal exposure to methadone via maternal osmotic minipumps on the expression of acetylcholinesterase (AChE) and choline acetyltransferase (ChAT) has been studied by light microscopy in the striatum of male and female rats.
Regulation (effect) of Gene_expression (expression) of choline acetyltransferase in striatum associated with methadone
2) Confidence 0.45 Published 1993 Journal Brain Res. Dev. Brain Res. Section Abstract Doc Link 8149590 Disease Relevance 0 Pain Relevance 0.32
20% increase; P = 0.004) compared to NL controls, while the levels of ChAT and BuChE remain unaltered (Fig. 2A–C).
Regulation (unaltered) of Gene_expression (levels) of ChAT
3) Confidence 0.31 Published 2008 Journal Brain Section Body Doc Link PMC2577805 Disease Relevance 0.68 Pain Relevance 0.03
In another study, memantine (5 mg/kg, i.p.) given at the onset of ischemia protected the rabbit retina from changes in GABA and ChAT immunoreactivities and induced a recovery of the reduced ?
Regulation (changes) of Gene_expression (immunoreactivities) of ChAT in retina associated with gaba and ischemia
4) Confidence 0.15 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2645549 Disease Relevance 0.66 Pain Relevance 0.32
Moreover, there is ChAT expression also in some lactotrophs (65, 66, 260, 594) and this expression may be affected by oestrogens, although this remains to be demonstrated.
Spec (may) Regulation (affected) of Gene_expression (expression) of ChAT in lactotrophs
5) Confidence 0.15 Published 2008 Journal Journal of Neuroendocrinology Section Body Doc Link PMC2229370 Disease Relevance 0.56 Pain Relevance 0.13

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox