INT57243

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Context Info
Confidence 0.69
First Reported 1993
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 10
Total Number 10
Disease Relevance 3.43
Pain Relevance 3.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SGCG) cytoskeleton (SGCG) cytoskeleton organization (SGCG)
cytoplasm (SGCG)
Anatomy Link Frequency
chondrocytes 2
osteoblasts 1
cerebral cortex 1
SGCG (Homo sapiens)
Pain Link Frequency Relevance Heat
Sumatriptan 7 100.00 Very High Very High Very High
Serotonin 2 100.00 Very High Very High Very High
nMDA receptor 2 99.78 Very High Very High Very High
cerebral cortex 1 99.08 Very High Very High Very High
melanocortin 1 receptor 9 98.26 Very High Very High Very High
depression 6 97.76 Very High Very High Very High
fluoxetine 3 97.40 Very High Very High Very High
gABA 4 92.64 High High
cytokine 9 77.68 Quite High
sSRI 1 69.20 Quite High
Disease Link Frequency Relevance Heat
Congenital Anomalies 1 99.24 Very High Very High Very High
Microphthalmia 2 98.96 Very High Very High Very High
Breast Cancer 25 98.88 Very High Very High Very High
Anxiety Disorder 16 98.28 Very High Very High Very High
Depression 6 97.76 Very High Very High Very High
Disease 18 93.04 High High
Repression 139 91.68 High High
Aggression 3 90.24 High High
Hypertension 1 88.20 High High
Coronary Artery Disease 1 87.52 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We confirmed a significant decrease in type II collagen and aggrecan mRNA expressions in chondrocytes by co-culture with osteoblasts after impact-loading, and significant increase in mRNA and protein expressions of IL-1beta in subchondral osteoblasts from impact-loaded subchondral bone.
Transcription (expressions) of type in osteoblasts
1) Confidence 0.69 Published 2009 Journal Ann Biomed Eng Section Abstract Doc Link 19381811 Disease Relevance 0.33 Pain Relevance 0.26
What intracranial tissues in humans contain sumatriptan-sensitive serotonin 5-HT1-type receptors?
Transcription (sumatriptan-sensitive) of type associated with sumatriptan and serotonin
2) Confidence 0.67 Published 1993 Journal Neurosci. Lett. Section Title Doc Link 8152617 Disease Relevance 0 Pain Relevance 0.70
The mRNA expressions of type II collagen, aggrecan, and type X collagen in chondrocytes were decreased significantly by the co-culture with osteoblasts pre-treated by IL-1beta, -6, and TNF-alpha.
Transcription (expressions) of type in chondrocytes
3) Confidence 0.67 Published 2009 Journal Ann Biomed Eng Section Abstract Doc Link 19381811 Disease Relevance 0.34 Pain Relevance 0.30
The mRNA expressions of type II collagen, aggrecan, and type X collagen in chondrocytes were decreased significantly by the co-culture with osteoblasts pre-treated by IL-1beta, -6, and TNF-alpha.
Transcription (expressions) of type in chondrocytes
4) Confidence 0.67 Published 2009 Journal Ann Biomed Eng Section Abstract Doc Link 19381811 Disease Relevance 0.34 Pain Relevance 0.38
N-methyl-D-aspartate receptor dependent transcriptional regulation of two calcium/calmodulin-dependent protein kinase type II isoforms in rodent cerebral cortex.
Transcription (transcriptional) of type in cerebral cortex associated with nmda receptor and cerebral cortex
5) Confidence 0.52 Published 2003 Journal Neuroscience Section Title Doc Link 14614906 Disease Relevance 0.30 Pain Relevance 0.16
The presence of the CATGTG motif suggests that MC1R gene expression may be regulated by a basic helix-loop-helix-leucine-zipper (bHLH-LZ) type transcription factor.
Transcription (transcription) of type associated with melanocortin 1 receptor
6) Confidence 0.52 Published 2002 Journal Life Sci. Section Abstract Doc Link 12204775 Disease Relevance 0.17 Pain Relevance 0.63
In addition, the expression of 5alpha-reductase Type I mRNA and protein was lower in socially-isolated mice than that in group-housed mice whereas 3alpha-HSD mRNA expression remained unchanged.
Transcription (expression) of Type
7) Confidence 0.52 Published 2001 Journal Brain Res. Brain Res. Rev. Section Abstract Doc Link 11744079 Disease Relevance 0.34 Pain Relevance 0.42
The interim results from this prospective clinical trial provides the first report of a statistically significant association between detection of mam mRNA in PBL and high grade breast tumors.
Transcription (detection) of mam associated with breast cancer
8) Confidence 0.44 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2292197 Disease Relevance 0.84 Pain Relevance 0
It is important to be aware that according to the description of the Type D person, the negative emotions of anger, anxiety, and depression are experienced consciously.
Transcription (description) of Type associated with depression and anxiety disorder
9) Confidence 0.20 Published 2007 Journal J Behav Med Section Body Doc Link PMC2080858 Disease Relevance 0.77 Pain Relevance 0.20
In order to generate a standard curve, we conducted real-time PCR of a known concentration of PCR-amplified Adenovirus Type 17 genomic template using Adenovirus Type 17-specific primers and found that we could detect as little as 10 copies/ml of template (data not shown).
Transcription (concentration) of Type
10) Confidence 0.03 Published 2007 Journal Virol J Section Body Doc Link PMC1950496 Disease Relevance 0 Pain Relevance 0

General Comments

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