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Context Info
Confidence 0.05
First Reported 1994
Last Reported 1994
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.67
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Creb1) extracellular region (Penk) nucleus (Creb1)
DNA binding (Creb1) transcription factor binding (Creb1)
Anatomy Link Frequency
hypothalamus 1
Creb1 (Mus musculus)
Penk (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 2 98.60 Very High Very High Very High
Disease Link Frequency Relevance Heat
Stress 8 99.20 Very High Very High Very High
Targeted Disruption 1 95.72 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Molecular mechanisms of stress-induced proenkephalin gene regulation: CREB interacts with the proenkephalin gene in the mouse hypothalamus and is phosphorylated in response to hyperosmolar stress.
CREB Binding (interacts) of proenkephalin gene in hypothalamus associated with stress and enkephalin
1) Confidence 0.05 Published 1994 Journal Mol. Endocrinol. Section Title Doc Link 8170480 Disease Relevance 0.67 Pain Relevance 0.20

General Comments

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