INT57385

Context Info Confidence 0.33 First Reported 1994 Last Reported 1994 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.59 Pain Relevance 0

mitochondrion (Creb1) signal transduction (PENK) extracellular region (PENK) nucleus (Creb1) DNA binding (Creb1) transcription factor binding (Creb1)

PENK (Homo sapiens) Creb1 (Mus musculus)

Pain Link Frequency Relevance Heat Enkephalin 2 25.00

Disease Link Frequency Relevance Heat Stress 8 93.28 Targeted Disruption 1 56.72

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In contrast, CREB formed specific complexes with both the proenkephalin enhancer and a cAMP- and calcium-regulated element (CaRE) within the c-fos gene.

proenkephalin Binding (complexes) of CREB

1) Confidence 0.33 Published 1994 Journal Mol. Endocrinol. Section Abstract Doc Link 8170480 Disease Relevance 0.59 Pain Relevance 0

General Comments

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