INT57592

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Context Info
Confidence 0.33
First Reported 1994
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 17
Total Number 17
Disease Relevance 9.49
Pain Relevance 4.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
plasma 1
Median nerve 1
TAs (Mus musculus)
Pain Link Frequency Relevance Heat
visual analogue scale 60 99.44 Very High Very High Very High
Pain 142 99.42 Very High Very High Very High
nerve block 8 99.26 Very High Very High Very High
lidocaine 1 99.20 Very High Very High Very High
Pain score 15 99.12 Very High Very High Very High
Lasting pain 33 98.64 Very High Very High Very High
Perioperative pain 114 97.80 Very High Very High Very High
Action potential 3 95.96 Very High Very High Very High
withdrawal 1 95.48 Very High Very High Very High
Glutamate 44 86.64 High High
Disease Link Frequency Relevance Heat
Hypoxia 126 99.52 Very High Very High Very High
Pain 190 99.42 Very High Very High Very High
Hernia 133 98.92 Very High Very High Very High
Post Operative Pain 114 97.80 Very High Very High Very High
Stress 86 97.16 Very High Very High Very High
Recurrence 69 96.38 Very High Very High Very High
Seroma 11 96.28 Very High Very High Very High
Postoperative Complications 13 91.48 High High
Paralysis 4 90.68 High High
Pneumoperitoneum 46 88.16 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The patient with persisting pain underwent relaparoscopy and removal of all eight TAS that provided complete pain relief.
Negative_regulation (removal) of TAS associated with pain
1) Confidence 0.33 Published 2007 Journal Hernia Section Body Doc Link PMC2231409 Disease Relevance 0.86 Pain Relevance 0.35
As long as no significant differences between the two fixation techniques are demonstrated on issues of recurrence, complications, and postoperative pain, the time difference we have measured might be an argument in favor of the DC technique, especially when mesh fixation would require a large number of TAS.



Negative_regulation (number) of TAS associated with perioperative pain and recurrence
2) Confidence 0.33 Published 2007 Journal Hernia Section Body Doc Link PMC2231409 Disease Relevance 0.68 Pain Relevance 0.10
As long as no significant differences between the two fixation techniques are demonstrated on issues of recurrence, complications, and postoperative pain, the time difference we have measured might be an argument in favor of the DC technique, especially when mesh fixation would require a large number of TAS.



Negative_regulation (number) of TAS associated with perioperative pain and recurrence
3) Confidence 0.33 Published 2007 Journal Hernia Section Abstract Doc Link PMC2231409 Disease Relevance 0.27 Pain Relevance 0.10
We previously found that removal of TAS implicated in the development of chronic pain after LVIHR does not always relieve the pain [14].
Negative_regulation (removal) of TAS associated with pain and lasting pain
4) Confidence 0.29 Published 2009 Journal Surg Endosc Section Body Doc Link PMC2869434 Disease Relevance 1.32 Pain Relevance 1.02
These patients underwent either removal of the TAS used to affix the mesh (n = 2) or removal of the entire mesh and insertion of a new mesh (n = 3).
Negative_regulation (removal) of TAS
5) Confidence 0.29 Published 2009 Journal Surg Endosc Section Body Doc Link PMC2869434 Disease Relevance 0.73 Pain Relevance 0.41
AS and NS mesh fixation required about the same number of TAS.
Negative_regulation (number) of TAS
6) Confidence 0.29 Published 2009 Journal Surg Endosc Section Body Doc Link PMC2869434 Disease Relevance 0.45 Pain Relevance 0.27
Two of the patients with mesh removal and one with TAS removal became symptom free.
Negative_regulation (removal) of TAS
7) Confidence 0.29 Published 2009 Journal Surg Endosc Section Body Doc Link PMC2869434 Disease Relevance 0.82 Pain Relevance 0.37
Because the number of TAS used was predominantly eight, no statistical analysis could be performed on the relation between TAS and postoperative pain.
Negative_regulation (number) of TAS associated with perioperative pain
8) Confidence 0.29 Published 2009 Journal Surg Endosc Section Body Doc Link PMC2869434 Disease Relevance 0.44 Pain Relevance 0.36
Our results on the reduced plasma TAS level of the indomethacin-administered mice revealed severe oxidative stress.
Negative_regulation (reduced) of TAS in plasma associated with stress
9) Confidence 0.13 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952312 Disease Relevance 0.31 Pain Relevance 0.08
TAS and uric acid levels were significantly decreased on postoperative day 1 in comparison to preoperative levels; however, no alterations to the concentrations of thiobarbituric acid-reactive substances were observed in the postoperative period in patients who underwent an open cholecystectomy.
Negative_regulation (decreased) of TAS
10) Confidence 0.09 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2845769 Disease Relevance 0.53 Pain Relevance 0
The mean loss of TAS was 70.3% in men and 74.3% in women.
Negative_regulation (loss) of TAS
11) Confidence 0.08 Published 1997 Journal J Hand Surg Am Section Abstract Doc Link 9330144 Disease Relevance 0.17 Pain Relevance 0.35
Median nerve block at the wrist resulted in a dramatic decrease in TAS in all volunteers.
Negative_regulation (decrease) of TAS in Median nerve associated with nerve block
12) Confidence 0.08 Published 1997 Journal J Hand Surg Am Section Abstract Doc Link 9330144 Disease Relevance 0.18 Pain Relevance 0.35
In our study, TOS levels in patients that underwent LC slightly increased during the perioperative period and on postoperative day 1, while TAS levels in this group slightly decreased; however, the changes in the levels of both TOS and TAS were not statistically significant.
Negative_regulation (decreased) of TAS
13) Confidence 0.07 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2845769 Disease Relevance 0.46 Pain Relevance 0
Mean and SD values of PON1 and arylesterase activities, as well as TAS and TOS levels are presented in Table 2.
Negative_regulation (presented) of TAS
14) Confidence 0.07 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2845769 Disease Relevance 0.16 Pain Relevance 0
Border zone TAs arose from these low-amplitude plateaus and were either eliminated by the addition of lidocaine to NL consistent with their presumed NL site of origin or occurred after localized withdrawal of EDTA from one segment in fibers rendered quiescent at the plateau by generalized superfusion with EDTA.
Negative_regulation (eliminated) of TAs associated with withdrawal and lidocaine
15) Confidence 0.05 Published 1994 Journal Am. Heart J. Section Abstract Doc Link 8197981 Disease Relevance 0.22 Pain Relevance 0.42
The decrease in TAS and increase in TBARS levels confirms that, there is an increased oxidative stress in anoxia and reperfusion.


Negative_regulation (decrease) of TAS associated with stress and hypoxia
16) Confidence 0.02 Published 2010 Journal International Journal of Medical Sciences Section Body Doc Link PMC2880843 Disease Relevance 0.96 Pain Relevance 0.18
In reperfusion groups the decrease of TAS was lesser than that of anoxia group.
Negative_regulation (decrease) of TAS associated with hypoxia
17) Confidence 0.02 Published 2010 Journal International Journal of Medical Sciences Section Body Doc Link PMC2880843 Disease Relevance 0.94 Pain Relevance 0.15

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