INT57599

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Context Info
Confidence 0.03
First Reported 1994
Last Reported 2002
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.00
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Btg1) enzyme binding (Btg1) cytoplasm (Btg1)
Anatomy Link Frequency
urine 1
Btg1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 1 92.04 High High
interstitial cystitis 6 50.00 Quite Low
cytokine 2 10.00 Low Low
Disease Link Frequency Relevance Heat
Hyperinsulinism 6 99.34 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

1 95.48 Very High Very High Very High
Insulin Resistance 6 94.76 High High
Microvascular Angina 1 92.04 High High
Coronary Artery Disease 6 90.76 High High
Metabolic Syndrome 2 88.76 High High
Syndrome 1 87.44 High High
Disorder Of Lipid Metabolism 1 76.48 Quite High
Endometriosis (extended) 1 75.60 Quite High
Hypertension 1 70.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: Certain markers were significantly increased in interstitial cystitis, including anti-proliferative factor, epidermal growth factor, insulin-like growth factor (IGF) binding protein-3 and interleukin (IL)-6.
Positive_regulation (increased) of anti-proliferative factor
1) Confidence 0.03 Published 2002 Journal J. Urol. Section Body Doc Link 11992058 Disease Relevance 0 Pain Relevance 0
CONCLUSIONS: This study confirmed several previously reported urine alterations in interstitial cystitis, including increased anti-proliferative factor, epidermal growth factor, IGF binding protein-3 and IL-6, and decreased heparin-binding epidermal growth factor-like growth factor and cyclic guanosine monophosphate.
Positive_regulation (increased) of anti-proliferative factor in urine
2) Confidence 0.03 Published 2002 Journal J. Urol. Section Body Doc Link 11992058 Disease Relevance 0 Pain Relevance 0
Increased insulin levels are also associated with increases in the anti-fibrinolytic factor, plasminogen activator inhibitor-I (PAI-I).
Positive_regulation (increases) of anti-fibrinolytic factor associated with hyperinsulinism
3) Confidence 0.00 Published 1994 Journal Int J Fertil Menopausal Stud Section Abstract Doc Link 8199641 Disease Relevance 1.91 Pain Relevance 0.09

General Comments

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