INT57626

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Context Info
Confidence 0.36
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.79
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (HRASLS)
HRASLS (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 6 99.00 Very High Very High Very High
Inflammation 40 91.68 High High
antagonist 19 83.00 Quite High
agonist 5 77.24 Quite High
depression 10 73.36 Quite High
alcohol 6 72.40 Quite High
Crohn's disease 30 71.44 Quite High
tolerance 9 69.24 Quite High
Pain 3 55.80 Quite High
Potency 25 47.12 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 38 98.80 Very High Very High Very High
Obesity 54 96.16 Very High Very High Very High
Thrombosis 2 95.64 Very High Very High Very High
Increased Venous Pressure Under Development 4 93.64 High High
Inflammatory Bowel Disease 70 86.88 High High
Renal Failure 1 84.88 Quite High
Radiation Sickness 1 81.20 Quite High
Depression 13 73.36 Quite High
Disease 43 71.44 Quite High
Diabetes Mellitus 85 71.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
G polymorphism creates a c-MYB binding site, which can activate COX-2 expression, and displays a higher promoter activity [15].
a c Binding (binding) of
1) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2991351 Disease Relevance 0.49 Pain Relevance 0.13
Glucocorticoids inhibit eicosanoid synthesis primarily by interfering with phospholipase A2 whilst non-steroidal anti-inflammatory drugs prevent prostaglandin/thromboxane synthesis by inhibiting cyclooxygenase.
phospholipase Binding (interfering) of associated with inflammation and cinod
2) Confidence 0.32 Published 1994 Journal Acta Oncol Section Abstract Doc Link 8204269 Disease Relevance 0.71 Pain Relevance 0.30
Regression analysis was used to measure the association between the S-TOFHLA score and each of our four outcomes (A1C, SBP, DBP, and LDL) after controlling for potentially confounding patient characteristics.
A1C Binding (association) of
3) Confidence 0.04 Published 2006 Journal BMC Fam Pract Section Body Doc Link PMC1559691 Disease Relevance 0.73 Pain Relevance 0.13
Indeed, pretreatment of 25 HCECs with 10 µM PCA-42481 followed by the addition of PAF (10 nM) resulted in minimal mobilization of [Ca2+]i (Figure 4A), indicating effective blockade of the PAF receptor and its subsequent coupling to phospholipase C.
phospholipase Binding (coupling) of
4) Confidence 0.04 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2693427 Disease Relevance 0 Pain Relevance 0.12
There was a tendency to a positive association between YKL-40 mRNA and A1C (P = 0.0645).
A1C Binding (association) of
5) Confidence 0.00 Published 2008 Journal Diabetes Section Body Doc Link PMC2570404 Disease Relevance 0.85 Pain Relevance 0.08

General Comments

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