INT57664

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Context Info
Confidence 0.19
First Reported 1994
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.41
Pain Relevance 2.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Npy2r)
Anatomy Link Frequency
DRG 2
neurons 1
Npy2r (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 2 99.72 Very High Very High Very High
c fibre 1 99.68 Very High Very High Very High
Spinal cord 6 98.04 Very High Very High Very High
Anterior cingulate 1 97.80 Very High Very High Very High
antidepressant 2 94.40 High High
Anterior cingulate cortex 1 93.48 High High
fluoxetine 5 92.80 High High
Serotonin 1 91.68 High High
Spinal nerve ligature 3 91.12 High High
Nucleus accumbens 2 90.16 High High
Disease Link Frequency Relevance Heat
Sprains And Strains 4 88.08 High High
Neuroma 3 87.84 High High
Nervous System Injury 12 83.76 Quite High
Neuropathic Pain 6 80.12 Quite High
Depression 4 78.60 Quite High
Nociception 2 73.12 Quite High
Injury 4 53.92 Quite High
Depressive Disorder 1 34.08 Quite Low
Pain 1 25.00 Low Low
Syndrome 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Receptor autoradiography indicated that small- and medium-diameter DRG somata of the C-fiber class normally express both Y1 and Y2 receptor subtypes.
Gene_expression (express) of Y2 receptor in DRG associated with c fibre
1) Confidence 0.19 Published 1999 Journal Pain Section Abstract Doc Link 10068164 Disease Relevance 0.33 Pain Relevance 0.23
Pharmacological experiments using selective Y1 and Y2 receptor antagonists suggest that Y2 is the prominent NPY receptor subtype expressed in trigeminal ganglia neurons, DRG neurons, and spinal cord.
Gene_expression (expressed) of Y2 in neurons associated with antagonist and spinal cord
2) Confidence 0.13 Published 1994 Journal J. Neurosci. Section Abstract Doc Link 8207499 Disease Relevance 0.31 Pain Relevance 0.67
Pharmacological experiments using selective Y1 and Y2 receptor antagonists suggest that Y2 is the prominent NPY receptor subtype expressed in trigeminal ganglia neurons, DRG neurons, and spinal cord.
Gene_expression (expressed) of Y2 in DRG associated with antagonist and spinal cord
3) Confidence 0.04 Published 1994 Journal J. Neurosci. Section Abstract Doc Link 8207499 Disease Relevance 0.31 Pain Relevance 0.67
Y2 mRNA expression levels did not differ between FSL and FRL animals.
Gene_expression (expression) of Y2 mRNA
4) Confidence 0.03 Published 1998 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 9729278 Disease Relevance 0.45 Pain Relevance 0.70

General Comments

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