INT57672

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Context Info
Confidence 0.15
First Reported 1994
Last Reported 2003
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.16
Pain Relevance 1.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

htr (Mus musculus)
Pain Link Frequency Relevance Heat
tramadol 7 100.00 Very High Very High Very High
fluoxetine 1 99.84 Very High Very High Very High
Endep 1 99.52 Very High Very High Very High
narcan 1 99.18 Very High Very High Very High
antagonist 4 98.98 Very High Very High Very High
antidepressant 5 98.76 Very High Very High Very High
opioid receptor 3 98.74 Very High Very High Very High
Morphine 1 95.60 Very High Very High Very High
Kappa opioid receptor 3 86.24 High High
Analgesic 1 82.08 Quite High
Disease Link Frequency Relevance Heat
Shock 2 83.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chronic administration of the antidepressants, trazodone, imipramine, amitriptyline, and fluoxetine had no effect on HTR, whereas administration of clorgyline attenuated HTR significantly. 5.
Neg (no) Regulation (effect) of HTR associated with antidepressant, endep and fluoxetine
1) Confidence 0.15 Published 1994 Journal Prog. Neuropsychopharmacol. Biol. Psychiatry Section Abstract Doc Link 8208989 Disease Relevance 0.16 Pain Relevance 0.35
Furthermore, the nonselective opioid receptor antagonists, naloxone and diprenorphine (M5050), reversed the effect of tramadol on 5-HTP-induced HTR dose-dependently.
Regulation (effect) of HTR associated with tramadol, antagonist, narcan and opioid receptor
2) Confidence 0.14 Published 2003 Journal Life Sci. Section Abstract Doc Link 12570923 Disease Relevance 0 Pain Relevance 1.32

General Comments

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