INT57822

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Context Info
Confidence 0.00
First Reported 1993
Last Reported 1993
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Slc25a2, Atxn2l) biological_process (Slc25a2, Atxn2l) transport (Slc25a2)
mitochondrion (Slc25a2)
Slc25a2 (Mus musculus)
Atxn2l (Mus musculus)
Slc25a2 - D95N (1)
Pain Link Frequency Relevance Heat
agonist 8 100.00 Very High Very High Very High
Enkephalin 5 100.00 Very High Very High Very High
opioid receptor 5 98.52 Very High Very High Very High
antagonist 3 92.48 High High
Pain 1 82.48 Quite High
Neurotransmitter 1 79.52 Quite High
Endogenous opioid 1 78.08 Quite High
MU agonist 1 66.16 Quite High
Buprenorphine 1 62.96 Quite High
mu opioid receptor 1 58.72 Quite High
Disease Link Frequency Relevance Heat
Pain 2 82.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The D95N mutant receptor had reduced affinity for delta receptor-selective agonists such as enkephalin, [D-Pen2,D-Pen5]enkephalin and [D-Ser2,Leu5]enkephalin-Thr6 such that it did not bind these peptides even at micromolar concentrations.
mutant receptor (D95N) Binding (affinity) of D-Pen2 associated with agonist and enkephalin
1) Confidence 0.00 Published 1993 Journal J. Biol. Chem. Section Abstract Doc Link 8226821 Disease Relevance 0.08 Pain Relevance 1.17

General Comments

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