INT57973

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Context Info
Confidence 0.67
First Reported 1993
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.23
Pain Relevance 1.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (ITGB1) plasma membrane (ITGB1)
Anatomy Link Frequency
lymphocytes 1
bone marrow 1
embryonic stem cells 1
T cells 1
ITGB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 7 99.72 Very High Very High Very High
Dopamine 12 99.56 Very High Very High Very High
agonist 3 80.00 Quite High
antagonist 3 79.48 Quite High
dopamine receptor 3 74.40 Quite High
Opioid 3 62.00 Quite High
withdrawal 2 47.76 Quite Low
Central nervous system 1 46.80 Quite Low
Migraine 1 36.64 Quite Low
Spinal cord 12 24.28 Low Low
Disease Link Frequency Relevance Heat
Death 7 93.88 High High
Apoptosis 4 93.44 High High
Adhesions 2 90.68 High High
Aging 9 90.36 High High
Hypoxia 35 87.88 High High
Congenital Anomalies 1 80.32 Quite High
Schizophrenia 1 39.04 Quite Low
Disease 10 37.96 Quite Low
Headache 1 36.64 Quite Low
Lifespan 2 26.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, monkeys exposed daily to morphine showed a 30% increase in the helper-inducer CD4+ lymphocytes, CD4+CD29+, compared to untreated controls.
Positive_regulation (increase) of CD29 in lymphocytes associated with morphine
1) Confidence 0.67 Published 1993 Journal Adv. Exp. Med. Biol. Section Abstract Doc Link 8237605 Disease Relevance 0.08 Pain Relevance 0.72
Based on immunofluorescence staining, T-MPCs and BM-MPCs were both positive for CD29, CD44, and CD105 and negative for CD14, CD34, and CD45 (Figure 2a).
Positive_regulation (positive) of CD29
2) Confidence 0.17 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575631 Disease Relevance 0 Pain Relevance 0
At flow cytometry analysis AM-hMSCs showed an immunophenotypical profile, i.e., positive for CD105, CD73, CD29, CD44, CD166 and negative for CD14, CD34, CD45, consistent with that reported for bone marrow-derived MSCs.
Positive_regulation (positive) of CD29 in bone marrow
3) Confidence 0.11 Published 2007 Journal BMC Dev Biol Section Abstract Doc Link PMC1810523 Disease Relevance 0 Pain Relevance 0
The phenotypic characteristics of the de-ATSC showed significantly increased CD90, CD29, CD44, CD117, and CD133 surface epitope-harboring populations and also they appeared gradually increased embryonic stem cells markers, such as Sox2, SSEA4, and TRA1-80 in the results of FACS and immunocytochemical analysis (Figure 1C and 1D).
Positive_regulation (increased) of CD29 in embryonic stem cells
4) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2817727 Disease Relevance 0.97 Pain Relevance 0
Dopamine interacts directly with its D3 and D2 receptors on normal human T cells, and activates beta1 integrin function.
Positive_regulation (activates) of beta1 integrin in T cells associated with dopamine
5) Confidence 0.04 Published 2001 Journal Eur. J. Immunol. Section Title Doc Link 11745370 Disease Relevance 0.18 Pain Relevance 0.72

General Comments

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