INT57983

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Context Info
Confidence 0.37
First Reported 1993
Last Reported 1993
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il1b, Crh) extracellular region (Il1b, Crh) aging (Il1b)
response to stress (Crh) cytoplasm (Crh)
Il1b (Rattus norvegicus)
Crh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 3 100.00 Very High Very High Very High
dexamethasone 1 96.88 Very High Very High Very High
narcan 4 89.92 High High
opiate 2 88.80 High High
Intracerebroventricular 1 73.12 Quite High
Hippocampus 1 67.28 Quite High
corticosteroid 1 43.84 Quite Low
Disease Link Frequency Relevance Heat
Acute-phase Reaction 1 92.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neither antiserum against corticotropin-releasing factor (CRF) nor the alpha-helical-CRF antagonist (25 micrograms/rat icv) affected IL-6 induction by central IL-1 beta, which, however, was significantly prevented by the synthetic glucocorticoid dexamethasone [3 mg/kg intraperitoneally (ip)].
IL-1 beta Neg (Neither) Regulation (affected) of CRF associated with antagonist and dexamethasone
1) Confidence 0.37 Published 1993 Journal Am. J. Physiol. Section Abstract Doc Link 8238440 Disease Relevance 0.09 Pain Relevance 0.44

General Comments

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