INT58140

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Context Info
Confidence 0.01
First Reported 1993
Last Reported 1993
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.40
Pain Relevance 1.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (AP2M1, Oprm1) transport (AP2M1) mitochondrion (AP2M1)
signal transducer activity (Oprm1) cytosol (AP2M1) lipid binding (AP2M1)
Anatomy Link Frequency
brainstem 1
AP2M1 (Homo sapiens)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
medulla 8 100.00 Very High Very High Very High
Central grey 5 94.24 High High
Analgesic 4 91.40 High High
Morphine 4 89.80 High High
Locus ceruleus 1 75.36 Quite High
analgesia 1 75.00 Quite High
Raphe magnus 1 71.32 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 5 94.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, these studies indicate the presence of intrinsic brainstem mu 1 receptor systems with synergistic interactions which can be pharmacologically distinguished from the brainstem mu 2 receptors mediating supraspinal/spinal synergy.
mu 2 Binding (interactions) of mu 1 receptor in brainstem associated with medulla
1) Confidence 0.01 Published 1993 Journal Brain Res. Section Abstract Doc Link 8252389 Disease Relevance 0.40 Pain Relevance 1.23

General Comments

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