INT58202

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Context Info
Confidence 0.37
First Reported 1993
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 2.49
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TFF1) extracellular region (TFF1) carbohydrate metabolic process (TFF1)
response to stress (TFF1)
Anatomy Link Frequency
bile 1
TFF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 7 100.00 Very High Very High Very High
Cholecystokinin 1 99.92 Very High Very High Very High
Dynorphin 1 99.02 Very High Very High Very High
Opioid 1 98.80 Very High Very High Very High
depression 1 83.44 Quite High
rheumatoid arthritis 1 73.52 Quite High
cytokine 2 67.28 Quite High
Paracetamol 1 65.84 Quite High
antidepressant 1 25.00 Low Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 1 99.00 Very High Very High Very High
Cancer 69 98.52 Very High Very High Very High
Aging 4 98.22 Very High Very High Very High
Appetite Loss 16 98.04 Very High Very High Very High
Recurrence 6 97.56 Very High Very High Very High
Depression 1 83.44 Quite High
Breast Cancer 23 80.60 Quite High
Rheumatoid Arthritis 1 73.52 Quite High
Syndrome 1 57.44 Quite High
Disease 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, letrozole was effective even in marginally ER+ tumors and, unlike tamoxifen, consistently reduced the expression from estrogen-regulated genes (progesterone receptor and trefoil factor 1).
Regulation (regulated) of trefoil factor 1 associated with cancer
1) Confidence 0.37 Published 2007 Journal Breast Cancer Res Treat Section Abstract Doc Link PMC2001223 Disease Relevance 0.47 Pain Relevance 0
In a prospective study comparing the efficacy of IVF and ICSI after TFF in a previous IVF attempt, the fertilization rate in a second cycle was significantly higher after ICSI than after IVF (48% respectively 11%, P < 0.001).
Regulation (efficacy) of TFF
2) Confidence 0.14 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2632644 Disease Relevance 0.27 Pain Relevance 0
Their effects on gastric emptying, postprandial circulating bile acids, triacylglycerols and gastrointestinal hormone levels were studied.
Regulation (effects) of gastrointestinal hormone in bile associated with bile
3) Confidence 0.07 Published 1993 Journal Br. J. Nutr. Section Abstract Doc Link 8260476 Disease Relevance 0.10 Pain Relevance 0.19
The physiological anorexia of aging is due to a decreased opioid (dynorphin) feeding drive and an increase in the satiating effect of the gastrointestinal hormone, cholecystokinin.
Regulation (effect) of gastrointestinal hormone associated with appetite loss, aging, dynorphin, cholecystokinin and opioid
4) Confidence 0.01 Published 1996 Journal Drugs Aging Section Abstract Doc Link 8845587 Disease Relevance 1.65 Pain Relevance 0.34

General Comments

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