INT58213

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Context Info
Confidence 0.42
First Reported 1993
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.13
Pain Relevance 1.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

carbohydrate metabolic process (Gusb) lysosome (Gusb)
Anatomy Link Frequency
urine 1
Gusb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
bradykinin 3 99.36 Very High Very High Very High
Morphine 13 95.88 Very High Very High Very High
Codeine 7 88.44 High High
Inflammation 4 80.24 Quite High
cINOD 1 75.44 Quite High
Potency 5 60.88 Quite High
opiate 1 52.08 Quite High
antagonist 5 50.00 Quite Low
Pain 4 50.00 Quite Low
transdermal 2 50.00 Quite Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 3 98.60 Very High Very High Very High
Respiratory Syncytial Virus 116 97.92 Very High Very High Very High
Fibromyalgia 6 87.00 High High
Toxicity 5 82.32 Quite High
INFLAMMATION 4 80.24 Quite High
Pain 2 50.00 Quite Low
Hypercalcemia 14 38.36 Quite Low
Cancer 9 5.00 Very Low Very Low Very Low
Multiple Myeloma 6 5.00 Very Low Very Low Very Low
Osteoporosis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Heroin that does not react with B-glucuronidase remains unhydrolyzed as the diacetylmorphine derivative.
B-glucuronidase Neg (not) Binding (react) of
1) Confidence 0.42 Published 1993 Journal J. Forensic Sci. Section Abstract Doc Link 8263474 Disease Relevance 0 Pain Relevance 1.44
METHODS: Liquid chromatography tandem mass spectrometry analytical technique was used to quantitate fentanyl and norfentanyl concentrations in spot urine specimens, after incubation with glucuronidase.
glucuronidase Binding (incubation) of in urine
2) Confidence 0.33 Published 2010 Journal J Opioid Manag Section Body Doc Link 20297612 Disease Relevance 0.08 Pain Relevance 0
There were also differences in its equilibration halflife, which was short for the inhibition of serum TxB2, intermediate for exudate PGE2 and beta-glucuronidase and longer for bradykinin-induced swelling.
beta-glucuronidase Binding (intermediate) of associated with pressure and volume under development and bradykinin
3) Confidence 0.07 Published 1996 Journal Res. Vet. Sci. Section Abstract Doc Link 8819190 Disease Relevance 0.43 Pain Relevance 0.25
Gene expression determined by Q-PCR was normalized to human GUS and ABL, and the relative expression is shown as a percentage compared to control cultures treated with M-CSF and RANKL.
GUS Binding (normalized) of
4) Confidence 0.03 Published 2010 Journal Calcif Tissue Int Section Body Doc Link PMC2964465 Disease Relevance 0.62 Pain Relevance 0.03

General Comments

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