INT58364

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.56
First Reported 1993
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 0.35
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (GHSR) signal transducer activity (GHSR)
Anatomy Link Frequency
neurons 2
plasma 1
GHSR (Homo sapiens)
Pain Link Frequency Relevance Heat
Clonidine 1 100.00 Very High Very High Very High
imagery 8 76.76 Quite High
nud 2 54.32 Quite High
Pain 2 53.28 Quite High
Disease Link Frequency Relevance Heat
Hypoglycemia 1 100.00 Very High Very High Very High
Growth Hormone Deficiency 1 71.36 Quite High
Hypopituitarism 1 69.52 Quite High
Dyspepsia 2 54.32 Quite High
Pain 2 53.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ghrelin induced Ca2+ transients in one third of the myenteric neurons, involving release of Ca2+ from intracellular stores and direct GHS-receptor activation.
Positive_regulation (activation) of GHS-receptor in neurons
1) Confidence 0.56 Published 2008 Journal Verh. K. Acad. Geneeskd. Belg. Section Abstract Doc Link 18630723 Disease Relevance 0.11 Pain Relevance 0.18
We demonstrated that ghrelin has a direct excitatory effect on myenteric neurons in situ via ghrelin receptor activation.
Positive_regulation (activation) of ghrelin receptor in neurons
2) Confidence 0.56 Published 2008 Journal Verh. K. Acad. Geneeskd. Belg. Section Abstract Doc Link 18630723 Disease Relevance 0 Pain Relevance 0.11
One patient had no response of hGH to hypoglycemia, clonidine and GHRP-1, but the plasma hGH rose to 10 micrograms/l after GHRH.
Neg (no) Positive_regulation (response) of GHRP-1 in plasma associated with hypoglycemia and clonidine
3) Confidence 0.29 Published 1993 Journal Acta Endocrinol. Section Abstract Doc Link 8279223 Disease Relevance 0.24 Pain Relevance 0.10

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox