INT5844

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Context Info
Confidence 0.25
First Reported 1986
Last Reported 2010
Negated 6
Speculated 0
Reported most in Abstract
Documents 14
Total Number 14
Disease Relevance 9.64
Pain Relevance 2.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Vim) structural molecule activity (Vim) plasma membrane (Vim)
cytoskeleton (Vim) nucleus (Vim) biological_process (Vim)
Anatomy Link Frequency
neocortex 4
vessels 2
epithelium 2
striatum 1
hippocampus 1
Vim (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 12 99.98 Very High Very High Very High
Enkephalin 6 99.62 Very High Very High Very High
Hippocampus 7 98.44 Very High Very High Very High
Central nervous system 4 94.92 High High
cva 3 91.12 High High
Pain 9 83.68 Quite High
abdominal pain 3 81.76 Quite High
dexamethasone 16 77.12 Quite High
headache 4 74.88 Quite High
midbrain 3 74.24 Quite High
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 9 99.98 Very High Very High Very High
Cancer 94 99.86 Very High Very High Very High
Giant Cell Tumors 3 96.40 Very High Very High Very High
Rhinitis 4 96.08 Very High Very High Very High
Sarcoma 13 95.96 Very High Very High Very High
Carcinoma 1 95.52 Very High Very High Very High
Malignant Neoplastic Disease 20 93.64 High High
Necrosis 7 91.64 High High
Hemorrhage 1 91.12 High High
Transient Ischemic Attack 3 91.04 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The tubular epithelium was positive for CAM 5.2, epithelial membrane antigen, carcinoembryonic staining, and vimentin immunostaining.
Positive_regulation (positive) of Gene_expression (immunostaining) of vimentin in epithelium
1) Confidence 0.25 Published 1993 Journal Am. J. Surg. Pathol. Section Abstract Doc Link 8214262 Disease Relevance 0.38 Pain Relevance 0.07
Immunohistochemical study showed that the atypical cells were strongly reactive for vimentin and negative for CD68, while the giant cells were immunoreactive for CD68, but negative for vimentin.
Positive_regulation (immunoreactive) of Neg (negative) Gene_expression (negative) of vimentin
2) Confidence 0.25 Published 2002 Journal Int. J. Clin. Oncol. Section Abstract Doc Link 12494256 Disease Relevance 0.69 Pain Relevance 0.08
By flow cytometry analysis (Figure 2A), the Vim409 plasmid drove eGFP expression as well as the ubiquitin-C promoter in the parent vector (pFUGW).
Positive_regulation (drove) of Gene_expression (plasmid) of Vim409
3) Confidence 0.25 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2765473 Disease Relevance 0 Pain Relevance 0
We show that 1) a large majority of the SON proliferative cells is associated with capillary vessels, 2) this proliferative response correlates with a progressive increase in density of the capillary network within the nucleus, and 3) SON capillary vessels exhibit an increased expression of nestin and vimentin, two markers of newly formed vessels.
Positive_regulation (increased) of Gene_expression (expression) of vimentin in vessels
4) Confidence 0.25 Published 2005 Journal BMC Neurosci Section Abstract Doc Link PMC1079868 Disease Relevance 0 Pain Relevance 0.04
Transient ischemia stimulates glial fibrillary acid protein and vimentin gene expression in the gerbil neocortex, striatum and hippocampus.
Positive_regulation (stimulates) of Gene_expression (expression) of vimentin in neocortex associated with ischemia, enkephalin and hippocampus
5) Confidence 0.13 Published 1992 Journal Brain Res. Mol. Brain Res. Section Title Doc Link 1317493 Disease Relevance 0.30 Pain Relevance 0.49
Immunoperoxidase studies for cytokeratins, epithelial membrane antigen, actin, myosin, desmin, and vimentin were also negative.
Positive_regulation (negative) of Neg (negative) Gene_expression (negative) of vimentin
6) Confidence 0.12 Published 1986 Journal Vet. Pathol. Section Abstract Doc Link 3962083 Disease Relevance 1.29 Pain Relevance 0.08
The tumor cells were all immunoreactive for vimentin, CD 34, and focally actin-positive in one case, but not for keratin, desmin, S-100 protein, carcinoembryonic antigen, alpha 1-ACT and F VIII-related antigen, supported a primitive mesenchymal origin. p53 protein was expressed in two of the malignant cases.
Positive_regulation (immunoreactive) of Neg (not) Gene_expression (positive) of vimentin associated with malignant neoplastic disease and cancer
7) Confidence 0.07 Published 1999 Journal Lung Cancer Section Abstract Doc Link 10100146 Disease Relevance 2.31 Pain Relevance 0.12
Transient ischemia stimulates glial fibrillary acid protein and vimentin gene expression in the gerbil neocortex, striatum and hippocampus.
Positive_regulation (stimulates) of in hippocampus Gene_expression (expression) of vimentin in neocortex associated with ischemia, enkephalin and hippocampus
8) Confidence 0.05 Published 1992 Journal Brain Res. Mol. Brain Res. Section Title Doc Link 1317493 Disease Relevance 0.30 Pain Relevance 0.49
Transient ischemia stimulates glial fibrillary acid protein and vimentin gene expression in the gerbil neocortex, striatum and hippocampus.
Positive_regulation (stimulates) of in striatum Gene_expression (expression) of vimentin in neocortex associated with ischemia, enkephalin and hippocampus
9) Confidence 0.05 Published 1992 Journal Brain Res. Mol. Brain Res. Section Title Doc Link 1317493 Disease Relevance 0.30 Pain Relevance 0.49
Immunohistochemistry, the neoplastic cells were consistently positive for vimentin only and negative for a variety of antibodies.
Positive_regulation (negative) of Neg (negative) Gene_expression (positive) of vimentin
10) Confidence 0.04 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC2920234 Disease Relevance 0.68 Pain Relevance 0
Immunohistochemical studies showed that the tumor cells expressed strong immunoreactivity for vimentin (VIM) and alpha1-antichymotrypsin (?
Positive_regulation (immunoreactivity) of Gene_expression (expressed) of vimentin associated with cancer
11) Confidence 0.04 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2887780 Disease Relevance 0.81 Pain Relevance 0
Immunohistochemical studies showed positive vimentin staining but negative reactions to epithelial membrane antigen, cytokeratin low molecular weight, cytokeratin high molecular weight, CD34 and S-100 protein.
Positive_regulation (reactions) of Neg (negative) Gene_expression (staining) of vimentin
12) Confidence 0.03 Published 2004 Journal J Chin Med Assoc Section Abstract Doc Link 15648288 Disease Relevance 1.14 Pain Relevance 0.16
Immunohistochemical studies showed positive vimentin staining but negative reactions to epithelial membrane antigen, cytokeratin low molecular weight, cytokeratin high molecular weight, CD34 and S-100 protein.
Positive_regulation (positive) of Neg (negative) Gene_expression (staining) of vimentin
13) Confidence 0.03 Published 2004 Journal J Chin Med Assoc Section Abstract Doc Link 15648288 Disease Relevance 1.14 Pain Relevance 0.16
Positive expression of vimentin (100%, 22/22) and negative expression of CD117 (0%, 5/5) were also detected.
Positive_regulation (Positive) of Gene_expression (expression) of vimentin
14) Confidence 0.01 Published 2010 Journal BMC Cancer Section Abstract Doc Link PMC2984427 Disease Relevance 0.31 Pain Relevance 0

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