INT58488

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.19
First Reported 1994
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 1.98
Pain Relevance 1.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Rorb) cellular_component (Rorb)
Anatomy Link Frequency
auditory cortex 2
striatum 2
lenses 2
granulosa cells 2
hippocampus 2
Rorb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 1 100.00 Very High Very High Very High
nMDA receptor 31 99.74 Very High Very High Very High
Hippocampus 10 98.88 Very High Very High Very High
Somatosensory cortex 1 98.28 Very High Very High Very High
rheumatoid arthritis 18 97.68 Very High Very High Very High
Neurotransmitter 4 95.44 Very High Very High Very High
cytokine 11 83.44 Quite High
Inflammation 14 82.44 Quite High
Glutamate 24 80.96 Quite High
opiate 2 70.04 Quite High
Disease Link Frequency Relevance Heat
Convulsion 2 99.06 Very High Very High Very High
Rheumatoid Arthritis 19 97.68 Very High Very High Very High
Schizophrenia 1 94.56 High High
Disease 4 93.88 High High
Arthritis 8 90.28 High High
Neurodegenerative Disease 4 88.56 High High
INFLAMMATION 18 82.44 Quite High
Necrosis 2 80.40 Quite High
Cancer 3 80.04 Quite High
Polycystic Ovary Syndrome 6 50.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Atypical and typical neuroleptic treatments induce distinct programs of transcription factor expression in the striatum.
Positive_regulation (induce) of Gene_expression (expression) of transcription factor in striatum
1) Confidence 0.19 Published 1996 Journal J. Comp. Neurol. Section Title Doc Link 8891947 Disease Relevance 0.09 Pain Relevance 0
Unlike in adult hippocampus, seizure activity caused by kainate treatment does not increase the transcription factor and opioid peptide gene expression in the hippocampi of P7 rats.
Neg (not) Positive_regulation (increase) of Gene_expression (expression) of transcription factor in hippocampus associated with convulsion, hippocampus and opioid
2) Confidence 0.08 Published 1994 Journal J. Neurochem. Section Abstract Doc Link 8294905 Disease Relevance 0.16 Pain Relevance 0.54
The synthesis is regulated mainly by the transcription factors NF-IL-6, CAAT-enhancer-binding protein (C/EBP)-?
Positive_regulation (-) of Gene_expression (factors) of transcription
3) Confidence 0.08 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656246 Disease Relevance 1.50 Pain Relevance 0.66
Transcription factor expression in regenerated lenses
Positive_regulation (lenses) of Gene_expression (expression) of Transcription factor in lenses
4) Confidence 0.03 Published 2010 Journal Molecular Vision Section Body Doc Link PMC2834568 Disease Relevance 0 Pain Relevance 0
For example, the expression level of RORbeta mRNA was higher in layers 2/3 of the Par1 subfield of the somatosensory cortex and the auditory cortex, which is consistent with the findings described in a previous report [8].
Positive_regulation (higher) of Gene_expression (expression) of RORbeta mRNA in auditory cortex associated with somatosensory cortex
5) Confidence 0.03 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2533703 Disease Relevance 0 Pain Relevance 0.05
We have previously demonstrated that rat mature Müller glia responds to NMDA receptor activation, inducing changes in transcription factor expression and function [13,14].
Positive_regulation (inducing) of Gene_expression (expression) of transcription factor associated with nmda receptor
6) Confidence 0.01 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2666774 Disease Relevance 0.17 Pain Relevance 0.35
It is not known however, what stimulates the expression of this transcription factor in granulosa cells, nor at what stage of follicular development expression of PPAR?
Positive_regulation (stimulates) of Gene_expression (expression) of transcription factor in granulosa cells
7) Confidence 0.01 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2795759 Disease Relevance 0.05 Pain Relevance 0.03

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox