INT58565

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Context Info
Confidence 0.03
First Reported 1993
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.98
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
cleavage 1
Bh4p (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 1 78.00 Quite High
cytokine 4 76.24 Quite High
ischemia 18 50.00 Quite Low
Inflammation 4 43.16 Quite Low
fibrosis 1 31.84 Quite Low
isoflurane 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Buprenorphine 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
halothane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Head Trauma 1 92.16 High High
Brain Injury 1 89.96 High High
Pollakiuria 1 80.00 Quite High
Pain 1 78.00 Quite High
Spasticity 1 76.56 Quite High
Phenylketonuria 3 75.00 Quite High
Neurologic Manifestations 2 75.00 Quite High
Injury 40 74.16 Quite High
Apoptosis 43 50.96 Quite High
Cv Unclassified Under Development 18 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since a BH4-domain containing peptide is generated by caspase cleavage of BCL2, it is likely that BH4-peptides are also released extracellularly [58].
Localization (released) of BH4 in cleavage
1) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2816997 Disease Relevance 0.44 Pain Relevance 0.04
Urinary secretion of endogenous tetrahydroxy-biopterin (BH4; coenzyme of Phe hydroxylase) remained in a normal range, and oral administration of 100 mg/kg of BH4 failed to normalize the serum Phe level.
Localization (secretion) of BH4
2) Confidence 0.01 Published 1993 Journal Rinsho Shinkeigaku Section Abstract Doc Link 8299276 Disease Relevance 0.55 Pain Relevance 0.08

General Comments

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