INT58566

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Context Info
Confidence 0.58
First Reported 1993
Last Reported 2007
Negated 3
Speculated 1
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 2.30
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pth) extracellular region (Pth) cellular_component (Pth)
Anatomy Link Frequency
parathyroid 2
Pth (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Restless leg syndrome 1 96.12 Very High Very High Very High
Dismenorea 3 88.20 High High
depression 1 82.08 Quite High
Pain 2 42.00 Quite Low
fibrosis 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 2 96.12 Very High Very High Very High
Hypercalcemia 77 93.24 High High
Hypocalcemia 5 91.68 High High
Osteogenesis Imperfecta 25 90.12 High High
Reprotox - General 1 3 88.20 High High
Osteoporosis 56 83.20 Quite High
Depression 1 82.08 Quite High
Hyperplasia 3 81.28 Quite High
Anxiety Disorder 1 81.12 Quite High
Fatigue 1 67.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Under normal conditions, calcitriol regulates the expression of PTH by suppressing transcription of pre-pro-PTH messenger RNA (Russell et al 1986; Silver et al 1986).
Regulation (regulates) of Gene_expression (expression) of PTH
1) Confidence 0.58 Published 2006 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1936265 Disease Relevance 0.50 Pain Relevance 0
There was no significant change in cortical volumetric BMD in either the PTH followed by ALN or PTH followed by Pcb groups.
Neg (no) Regulation (change) of Gene_expression (followed) of PTH
2) Confidence 0.44 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2684083 Disease Relevance 0 Pain Relevance 0
There was no significant change in cortical volumetric BMD in either the PTH followed by ALN or PTH followed by Pcb groups.
Neg (no) Regulation (change) of Gene_expression (followed) of PTH
3) Confidence 0.39 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2684083 Disease Relevance 0 Pain Relevance 0
In the present double blind study, we examined the effect of either ethylenediaminetetraacetatic acid (EDTA) or placebo on serum levels of PTH and biochemical markers of bone turnover in 15 women and 39 men (aged 41 to 81 years) suffering intermittent claudication due to atherosclerosis.
Spec (examined) Regulation (effect) of Gene_expression (levels) of PTH associated with restless leg syndrome and increased venous pressure under development
4) Confidence 0.25 Published 1993 Journal Dan Med Bull Section Abstract Doc Link 8299406 Disease Relevance 0.28 Pain Relevance 0.10
The biochemical parameters including calcium, phosphorus, alkaline phosphatase, PTH, and osteocalcin levels did not altered significantly in this study.
Neg (not) Regulation (altered) of Gene_expression (levels) of PTH
5) Confidence 0.11 Published 2007 Journal Journal of Korean Medical Science Section Body Doc Link PMC2693583 Disease Relevance 0.81 Pain Relevance 0
Estrogen regulates calcium metabolism, intestinal calcium absorption and parathyroid gene expression and secretion, triggering fluctuations across the menstrual cycle.
Regulation (regulates) of Gene_expression (expression) of parathyroid gene in parathyroid
6) Confidence 0.05 Published 2000 Journal J Am Coll Nutr Section Abstract Doc Link 10763903 Disease Relevance 0.71 Pain Relevance 0.28

General Comments

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