INT58580

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Context Info
Confidence 0.43
First Reported 1994
Last Reported 1997
Negated 1
Speculated 0
Reported most in Title
Documents 2
Total Number 3
Disease Relevance 0
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RPA1) chromosome organization (RPA1) nucleolus (RPA1)
nucleus (RPA1) DNA binding (RPA1) cytoplasm (RPA1)
RPA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 1 99.12 Very High Very High Very High
antagonist 5 93.16 High High
Morphine 4 90.40 High High
addiction 2 46.00 Quite Low
tolerance 2 45.40 Quite Low
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Morphine Dependence 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Characterization of a nuclear factor that enhances DNA binding activity of SSCRE-BP/PUR alpha, a single-stranded DNA binding protein.
Positive_regulation (enhances) of single-stranded DNA binding protein Binding (binding) of
1) Confidence 0.43 Published 1997 Journal Neurochem. Int. Section Title Doc Link 9185164 Disease Relevance 0 Pain Relevance 0.09
Characterization of a nuclear factor that enhances DNA binding activity of SSCRE-BP/PUR alpha, a single-stranded DNA binding protein.
Positive_regulation (enhances) of single-stranded DNA binding protein Binding (activity) of
2) Confidence 0.43 Published 1997 Journal Neurochem. Int. Section Title Doc Link 9185164 Disease Relevance 0 Pain Relevance 0.09
In addition, a nearby residue, histidine 265 of the human receptor, is required for the binding of RP67580 but not CP-96,345 or substance P.
Neg (not) Positive_regulation (required) of RP67580 Binding (binding) of associated with substance p
3) Confidence 0.01 Published 1994 Journal J. Biol. Chem. Section Abstract Doc Link 8300604 Disease Relevance 0 Pain Relevance 0.20

General Comments

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