INT58591

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Context Info
Confidence 0.42
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.46
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (PLG) extracellular space (PLG) extracellular region (PLG)
plasma membrane (PLG)
Anatomy Link Frequency
lungs 2
PLG (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 82 84.80 Quite High
antagonist 2 84.40 Quite High
headache 2 72.96 Quite High
Inflammatory response 2 63.96 Quite High
Somatostatin 4 63.76 Quite High
metalloproteinase 9 55.12 Quite High
cva 9 53.36 Quite High
Inflammation 50 50.72 Quite High
Analgesic 1 18.24 Low Low
cINOD 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cystitis 71 95.40 Very High Very High Very High
Amyloid Plaque 7 94.32 High High
Colon Cancer 1 90.20 High High
Keloid Scars 12 89.64 High High
Hemorrhage 18 85.60 High High
Pulmonary Fibrosis 63 84.80 Quite High
Choristoma 1 84.00 Quite High
Pressure And Volume Under Development 3 81.96 Quite High
Hematuria 30 81.28 Quite High
Diabetes Mellitus 1 74.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
If this finding can be extrapolated to lungs, it may suggest that lung fibroblasts could also participate in the synthesis of the major negative physiologic regulator of plasmin activation and, consequently, in the excessive alveolar fibrin accumulation [43].


Negative_regulation (regulator) of Positive_regulation (activation) of plasmin in lungs
1) Confidence 0.42 Published 2002 Journal Respir Res Section Body Doc Link PMC64814 Disease Relevance 0.72 Pain Relevance 0.23
Administration of gamma interferon in human subjects decreases plasminogen activation and fibrinolysis without influencing C1 inhibitor.
Negative_regulation (decreases) of Positive_regulation (activation) of plasminogen
2) Confidence 0.23 Published 1994 Journal J. Lab. Clin. Med. Section Title Doc Link 8301199 Disease Relevance 0.52 Pain Relevance 0.07
Stimulation of plasminogen through tPA (tissue plasminogen activator) and the subsequent generation of plasmin reduces ?
Negative_regulation (reduces) of Positive_regulation (Stimulation) of plasminogen
3) Confidence 0.03 Published 2009 Journal The Open Neurology Journal Section Body Doc Link PMC2684708 Disease Relevance 0.48 Pain Relevance 0.15
E-aminocaproic acid inhibits fibrinolysis by preventing the activation of plasminogen to plasmin.
Negative_regulation (preventing) of Positive_regulation (activation) of plasminogen
4) Confidence 0.02 Published 2010 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2938536 Disease Relevance 0.75 Pain Relevance 0.06

General Comments

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