INT586

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Context Info
Confidence 0.64
First Reported 1975
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.69
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Lipa) cell morphogenesis (Lipa) lipid metabolic process (Lipa)
lysosome (Lipa)
Anatomy Link Frequency
nucleus 1
Lipa (Mus musculus)
Pain Link Frequency Relevance Heat
trigeminal ganglion 3 92.08 High High
Hsan 2 83.48 Quite High
Bile 2 37.40 Quite Low
Inflammation 12 5.00 Very Low Very Low Very Low
Central nervous system 8 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Enkephalin 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 4 96.32 Very High Very High Very High
Atherosclerotic Plaque 10 91.36 High High
Dystonia 2 83.88 Quite High
Hereditary Sensory And Autonomic Neuropathies 2 83.48 Quite High
Atherosclerosis 34 80.56 Quite High
Disease 82 80.00 Quite High
Frailty 1 73.04 Quite High
Neurodegenerative Disease 2 50.48 Quite High
Dementia 2 42.40 Quite Low
Toxicity 12 34.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Subsequent to this observation, numerous neurones showed central chromatolysis, eccentric nucleus and increased lysosomal hydrolase activity.
Positive_regulation (increased) of lysosomal hydrolase in nucleus
1) Confidence 0.64 Published 1975 Journal Acta Neuropathol. Section Abstract Doc Link 52273 Disease Relevance 0.82 Pain Relevance 0.28
It has been theorized that oxLDL could accentuate accumulation of CE through inactivation of lysosomal acid lipase (LAL).
Positive_regulation (inactivation) of LAL
2) Confidence 0.17 Published 2009 Journal Microb Cell Fact Section Body Doc Link PMC2674406 Disease Relevance 0.44 Pain Relevance 0
It has been theorized that oxLDL could accentuate accumulation of CE through inactivation of lysosomal acid lipase (LAL).
Positive_regulation (inactivation) of lysosomal acid lipase
3) Confidence 0.17 Published 2009 Journal Microb Cell Fact Section Body Doc Link PMC2674406 Disease Relevance 0.44 Pain Relevance 0

General Comments

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