INT58632

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Context Info
Confidence 0.13
First Reported 1993
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 3.50
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il1f5) extracellular region (Il1f5) molecular_function (Il1f5)
biological_process (Il1f5)
Il1f5 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 17 99.62 Very High Very High Very High
dexamethasone 1 98.68 Very High Very High Very High
Arthritis 2 98.64 Very High Very High Very High
Hyperalgesia 1 98.60 Very High Very High Very High
cytokine 11 98.36 Very High Very High Very High
antagonist 3 92.80 High High
cINOD 1 91.80 High High
Serotonin 1 90.80 High High
Inflammatory response 1 85.96 High High
depression 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 16 99.62 Very High Very High Very High
Crystal Associated Disease 4 98.88 Very High Very High Very High
Synovitis 1 98.82 Very High Very High Very High
Pressure And Volume Under Development 4 98.64 Very High Very High Very High
Hyperalgesia 1 98.60 Very High Very High Very High
Urological Neuroanatomy 3 98.24 Very High Very High Very High
Anaphylaxis 2 91.20 High High
Myocarditis 48 85.96 High High
Left Ventricular Dysfunction 2 80.28 Quite High
Death 2 77.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A glucocorticoid (dexamethasone), two cyclooxygenase inhibitors (indomethacin, piroxicam) and an interleukin-1 (IL-1) release inhibitor (IX 207-887, Sandoz) all reduced edema and MPO activity as well.
Negative_regulation (inhibitor) of interleukin-1 associated with pressure and volume under development, urological neuroanatomy and dexamethasone
1) Confidence 0.13 Published 1993 Journal Agents Actions Section Abstract Doc Link 8304241 Disease Relevance 0.98 Pain Relevance 0.47
Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis.
Negative_regulation (inhibition) of interleukin 1 associated with hyperalgesia, inflammation, synovitis, crystal associated disease and arthritis
2) Confidence 0.05 Published 2009 Journal Ann. Rheum. Dis. Section Title Doc Link 19528034 Disease Relevance 0.59 Pain Relevance 0.34
The former was showed to suppress interleukin-1 and 6 and the latter suppresses interleukin-1?
Negative_regulation (suppress) of interleukin-1
3) Confidence 0.05 Published 2010 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2887330 Disease Relevance 1.00 Pain Relevance 0.08
The former was showed to suppress interleukin-1 and 6 and the latter suppresses interleukin-1?
Negative_regulation (suppresses) of interleukin-1
4) Confidence 0.05 Published 2010 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2887330 Disease Relevance 0.93 Pain Relevance 0.08

General Comments

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