INT58755

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.34
First Reported 1994
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 3.09
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (PAM) lyase activity (PAM) extracellular region (PAM)
Anatomy Link Frequency
hip 2
macrophages 1
conjunctiva 1
PAM (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropeptide 5 99.88 Very High Very High Very High
cytokine 24 99.68 Very High Very High Very High
Calcitonin gene-related peptide 4 99.24 Very High Very High Very High
Somatostatin 3 98.64 Very High Very High Very High
substance P 3 98.08 Very High Very High Very High
Enkephalin 3 97.40 Very High Very High Very High
cryotherapy 18 67.44 Quite High
topical agent 11 35.16 Quite Low
Inflammation 13 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Freckles 49 100.00 Very High Very High Very High
Melanoma 58 99.36 Very High Very High Very High
Nevus 20 97.20 Very High Very High Very High
Aggression 1 81.76 Quite High
Pigment Disorder 1 80.80 Quite High
Malignant Neoplastic Disease 22 79.24 Quite High
Disease 32 79.04 Quite High
Death 3 74.00 Quite High
Mycobacterial Infection 27 71.92 Quite High
Gallstones 1 70.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Malignant melanoma of the conjunctiva is commonly associated with PAM with atypia, although it can also arise de novo or from conjunctival nevi (Folberg et al 1985a).
PAM Binding (associated) of in conjunctiva associated with melanoma, nevus and freckles
1) Confidence 0.34 Published 2008 Journal Clinical ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2694026 Disease Relevance 1.46 Pain Relevance 0.03
The PAM can be attached easily to a belt and is worn on the right hip.
PAM Binding (attached) of in hip
2) Confidence 0.32 Published 2005 Journal BMC Public Health Section Body Doc Link PMC1351198 Disease Relevance 0 Pain Relevance 0
1. placing the PAM on the hip;
PAM Binding (placing) of in hip
3) Confidence 0.32 Published 2005 Journal BMC Public Health Section Body Doc Link PMC1351198 Disease Relevance 0 Pain Relevance 0
SO demonstrated immunoreactivity for VIP, PHI (PHM), neuropeptide Y, CGRP, galanin, somatostatin, substance P, and enkephalin, but no immunoreactivity was observed for bombesin.
PHM Binding (immunoreactivity) of associated with somatostatin, neuropeptide, enkephalin, substance p and calcitonin gene-related peptide
4) Confidence 0.18 Published 1994 Journal Dig. Dis. Sci. Section Abstract Doc Link 8313811 Disease Relevance 0.51 Pain Relevance 0.79
PAM has an insidious onset, and waxes and wanes.
PAM Binding (waxes) of
5) Confidence 0.07 Published 2009 Journal Oman Journal of Ophthalmology Section Body Doc Link PMC3018103 Disease Relevance 1.05 Pain Relevance 0
While TLR2 regulation may be due to Pam3Cys ligation and/or cytokine production from macrophages or other cellular subsets within the bronchoalveolar cells (5-8% are lymphocytes), regulation of TLR4 expression may result from a direct effect of LPS on the cell membrane as it was noted already within 10 minutes of LPS stimulation.
Pam3Cys Binding (ligation) of in macrophages associated with cytokine
6) Confidence 0.00 Published 2010 Journal Respir Res Section Body Doc Link PMC2817655 Disease Relevance 0.07 Pain Relevance 0.15

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox