INT58761

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Context Info
Confidence 0.26
First Reported 1993
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 1.54
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (CD1D) histone binding (CD1D) plasma membrane (CD1D)
cytoplasm (CD1D)
Anatomy Link Frequency
Langerhans cells 1
trigeminal nerve 1
CD1D (Homo sapiens)
Pain Link Frequency Relevance Heat
fifth nerve 1 99.50 Very High Very High Very High
antagonist 30 99.32 Very High Very High Very High
cytokine 186 98.76 Very High Very High Very High
Pain 5 98.72 Very High Very High Very High
Inflammation 36 92.88 High High
imagery 1 91.84 High High
dexamethasone 12 91.12 High High
headache 1 90.04 High High
Catecholamine 48 5.00 Very Low Very Low Very Low
cocaine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Langerhans-cell Histiocytosis 6 98.94 Very High Very High Very High
Pain 5 98.72 Very High Very High Very High
Cancer 4 96.16 Very High Very High Very High
INFLAMMATION 36 92.88 High High
Disease 9 91.84 High High
Fatigue 1 90.96 High High
Appetite Loss 1 90.44 High High
Headache 1 90.04 High High
Nociception 1 87.36 High High
Stress 39 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Light microscopy showed LCH, and immunohistochemical studies revealed S-100 and CD1a immunoreactivity in the Langerhans cells.
Regulation (immunoreactivity) of CD1a in Langerhans cells associated with langerhans-cell histiocytosis
1) Confidence 0.26 Published 2004 Journal Brain Tumor Pathol Section Abstract Doc Link 15700840 Disease Relevance 0.90 Pain Relevance 0.14
We explore the relationship between the threshold (th) of R3 and that of pain on stimulation of the trigeminal nerve and the extent to which R3 is modulated by habituation and attentional levels.
Regulation (modulated) of R3 in trigeminal nerve associated with pain and fifth nerve
2) Confidence 0.24 Published 1993 Journal Ital J Neurol Sci Section Abstract Doc Link 8314675 Disease Relevance 0.45 Pain Relevance 0.48
-induced HMC-1 is down regulated by NF-?
Regulation (regulated) of HMC-1
3) Confidence 0.01 Published 2004 Journal BMC Immunol Section Body Doc Link PMC521685 Disease Relevance 0 Pain Relevance 0.23
-induced HMC-1 is down regulated by adrenoceptor antagonists
Regulation (regulated) of HMC-1 associated with antagonist
4) Confidence 0.01 Published 2004 Journal BMC Immunol Section Body Doc Link PMC521685 Disease Relevance 0 Pain Relevance 0.18
-induced HMC-1 is down regulated by immunosuppressants
Regulation (regulated) of HMC-1
5) Confidence 0.01 Published 2004 Journal BMC Immunol Section Body Doc Link PMC521685 Disease Relevance 0.18 Pain Relevance 0.31

General Comments

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