INT58861

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Context Info
Confidence 0.25
First Reported 1993
Last Reported 2005
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.10
Pain Relevance 1.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ldha) mitochondrion (Ldha) oxidoreductase activity (Ldha)
carbohydrate metabolic process (Ldha) cytoplasm (Ldha)
Ldha (Mus musculus)
Pain Link Frequency Relevance Heat
ketamine 15 99.98 Very High Very High Very High
Enkephalin 9 99.82 Very High Very High Very High
anesthesia 1 77.56 Quite High
cytokine 1 25.00 Low Low
Inflammation 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Death 1 99.60 Very High Very High Very High
INFLAMMATION 1 25.00 Low Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When the administered concentration reached 1000 microM, ketamine caused a release of lactate dehydrogenase and cell death.
Positive_regulation (caused) of Localization (release) of lactate dehydrogenase associated with ketamine and death
1) Confidence 0.25 Published 2005 Journal Toxicol. Appl. Pharmacol. Section Abstract Doc Link 15781291 Disease Relevance 0.10 Pain Relevance 0.56
MENK did not elicit any significant extracellular release of lactate dehydrogenase (LDH) either, indicating that, under the experimental conditions described, the cells remained intact.
Neg (not) Positive_regulation (elicit) of Localization (release) of lactate dehydrogenase associated with enkephalin
2) Confidence 0.23 Published 1993 Journal Biomed. Pharmacother. Section Abstract Doc Link 8329664 Disease Relevance 0 Pain Relevance 0.70

General Comments

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