INT58866

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Context Info
Confidence 0.08
First Reported 1993
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.13
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Neu1) plasma membrane (Neu1) lysosome (Neu1)
Neu1 (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 9 98.56 Very High Very High Very High
cytokine 17 5.00 Very Low Very Low Very Low
agonist 9 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 203 99.80 Very High Very High Very High
Influenza Virus Infection 28 99.80 Very High Very High Very High
Sprains And Strains 21 98.44 Very High Very High Very High
Colon Cancer 1 86.56 High High
Malignant Neoplastic Disease 4 78.08 Quite High
Immunization 76 75.00 Quite High
Ovarian Cancer 6 17.52 Low Low
Infection 17 5.00 Very Low Very Low Very Low
Skin Cancer 16 5.00 Very Low Very Low Very Low
Weight Loss 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Rolf Kiessling (Karolinska Institute, Stockholm, Sweden) opened the Colloquium delivering the keynote lecture about: "The Her-2/neu gene as a target for tumor vaccination".
Regulation (target) of neu associated with cancer
1) Confidence 0.08 Published 2004 Journal J Transl Med Section Body Doc Link PMC441417 Disease Relevance 0.48 Pain Relevance 0
Moreover, MENK in concentrations of 10(-12) M, 10(-8) M, 10(-6) M or 10(-4) M did not change the activities of the lysosomal enzyme markers AP or BG in vitro.
Neg (not) Regulation (change) of lysosomal enzyme associated with enkephalin
2) Confidence 0.03 Published 1993 Journal Biomed. Pharmacother. Section Abstract Doc Link 8329664 Disease Relevance 0 Pain Relevance 0.75
Conventional influenza vaccines targeting the highly variable surface glycoproteins hemagglutinin and neuraminidase must antigenically match the emerging strain to be effective.
Regulation (targeting) of neuraminidase associated with influenza virus infection and sprains and strains
3) Confidence 0.02 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2953831 Disease Relevance 0.65 Pain Relevance 0

General Comments

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