INT58883

Context Info Confidence 0.63 First Reported 1993 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 12 Total Number 12 Disease Relevance 2.56 Pain Relevance 0.71

Anatomy Link Frequency ganglia 2 row 1 FB2 1 crops 1 T2 (Mus musculus)

Pain Link Frequency Relevance Heat Rsd 6 80.00 ganglionectomy 8 75.44 Pain 4 74.08 abdominal pain 7 55.76 anesthesia 1 28.52 Dopamine 7 7.68 cva 21 7.04 Central nervous system 14 5.00 headache 14 5.00 depression 7 5.00

Disease Link Frequency Relevance Heat Poisoning 21 95.48 Cancer 84 89.12 Pneumothorax 2 85.96 Intraoperative Complications 2 83.28 Complex Regional Pain Syndromes 6 80.00 Death 42 78.40 Skin Appendage Disease 6 77.88 Pain 4 74.08 Toxicity 147 71.52 Scrapie 56 62.64

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The T-2 and T-3 ganglia were grasped with forceps and excised.

Gene_expression (grasped) of T-2 in ganglia

1) Confidence 0.63 Published 1993 Journal J. Neurosurg. Section Abstract Doc Link 8331407 Disease Relevance 0.52 Pain Relevance 0.33

The T-2 and T-3 ganglia were grasped with forceps and excised.

Gene_expression (excised) of T-2 in ganglia

2) Confidence 0.63 Published 1993 Journal J. Neurosurg. Section Abstract Doc Link 8331407 Disease Relevance 0.52 Pain Relevance 0.33

Western blot analysis was carried out as described previously with monoclonal antibodies (mabs) T2 [23], SAF-84 (SPI bio), and P4 (R-Biopharm AG).

Gene_expression (described) of T2

3) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2982847 Disease Relevance 0.24 Pain Relevance 0

The operant saccades to T1 or T2 targets can vary slightly from trial to trial in latency, amplitude, velocity and accuracy.

Gene_expression (targets) of T2

4) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824817 Disease Relevance 0 Pain Relevance 0

As there are two reward magnitudes (H and L) to be assigned to each of two target locations (T1 and T2), there were four reward conditions overall, schematized by the vertical row of panels in Figure 1: 1) the LL condition in which both targets were blue, 2) the HH condition in which both targets were red, 3) the HL condition, in which T1 was red and T2 was blue, and 4) the LH condition which was the mirror of the HL condition.

Gene_expression (blue) of T2 in row

5) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2824817 Disease Relevance 0 Pain Relevance 0

T-2 and HT-2 are generally found in various cereal crops such as wheat, corn, barley, oats and rye and processed grains (malt, beer and bread) [84].

Gene_expression (found) of T-2 in crops

6) Confidence 0.01 Published 2008 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2635619 Disease Relevance 0.66 Pain Relevance 0.06

Between 2003 and 2005, the studies of DON, T-2 toxin, ZEA and fumonisins (FB1+FB2+FB3) in cereal samples collected from European and Mediterranean markets and Asian-Pacific region have been reported by Binder et al [133].

Gene_expression (studies) of T-2 in FB2

7) Confidence 0.01 Published 2008 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2635619 Disease Relevance 0 Pain Relevance 0

T-2 is produced by various species of Fusaria which are widespread fungi on a variety of plants in soil throughout the cold-temperate regions [81].

Gene_expression (produced) of T-2

8) Confidence 0.01 Published 2008 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2635619 Disease Relevance 0 Pain Relevance 0

In both event, isolates of F. sporotrichioides isolated from grains and beans were found to produce T-2 and its derivatives [78].

Gene_expression (produce) of T-2

9) Confidence 0.01 Published 2008 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2635619 Disease Relevance 0.18 Pain Relevance 0

T-2 and HT-2 have been reported to be produced by F. sporotrichioides, F. poae, F. equiseti and F. acuminatum [5].

Gene_expression (produced) of T-2

10) Confidence 0.01 Published 2008 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2635619 Disease Relevance 0.16 Pain Relevance 0

T-2 is a secondary metabolite produced by Fusarium and related fungal species [79].

Gene_expression (produced) of T-2

11) Confidence 0.01 Published 2008 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2635619 Disease Relevance 0.15 Pain Relevance 0

F. sporotrichioides of the Sporotrichiella section is the most important producer of T-2.

Gene_expression (producer) of T-2

12) Confidence 0.01 Published 2008 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2635619 Disease Relevance 0.13 Pain Relevance 0

General Comments

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