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Context Info
Confidence 0.44
First Reported 1993
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.86
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (AMPD1) small molecule metabolic process (AMPD1)
Anatomy Link Frequency
skeletal muscle 2
AMPD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 3 87.40 High High
ischemia 6 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Purine Or Pyrimidine Metabolism 4 100.00 Very High Very High Very High
Acidosis 1 95.96 Very High Very High Very High
Myalgia 3 87.40 High High
Rhabdomyolysis 4 85.72 High High
Myoglobinuria 1 82.24 Quite High
Increased Venous Pressure Under Development 18 6.08 Low Low
Cv Unclassified Under Development 6 5.00 Very Low Very Low Very Low
Fatigue 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Less accumulation of substrate for AMP deaminase or specific inactivation of AMP deaminase both could explain stabilization of the adenine nucleotide pool and reduced ammonia production [27].
Positive_regulation (accumulation) of Negative_regulation (inactivation) of AMP deaminase
1) Confidence 0.44 Published 2005 Journal BMC Physiol Section Body Doc Link PMC1187899 Disease Relevance 0.10 Pain Relevance 0
The girl was found to be homozygous for the C 34-T mutation of the AMPD1 gene causing primary myoadenylate deaminase deficiency in skeletal muscle.
Positive_regulation (causing) of Negative_regulation (deficiency) of myoadenylate deaminase in skeletal muscle associated with disorder of purine or pyrimidine metabolism
2) Confidence 0.37 Published 1993 Journal Eur. J. Pediatr. Section Abstract Doc Link 8335021 Disease Relevance 0.76 Pain Relevance 0.17

General Comments

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