INT58931

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Context Info
Confidence 0.34
First Reported 1993
Last Reported 2008
Negated 2
Speculated 0
Reported most in Body
Documents 11
Total Number 11
Disease Relevance 4.47
Pain Relevance 1.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (NAGLU) lysosome (NAGLU)
Anatomy Link Frequency
plasma 2
blood 1
urine 1
NAGLU (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory marker 4 99.56 Very High Very High Very High
qutenza 15 98.32 Very High Very High Very High
cINOD 26 96.92 Very High Very High Very High
headache 1 79.36 Quite High
Serotonin 2 77.36 Quite High
alcohol 18 71.16 Quite High
Restless leg syndrome 60 50.00 Quite Low
aspirin 11 50.00 Quite Low
Inflammation 9 50.00 Quite Low
Pain 4 36.16 Quite Low
Disease Link Frequency Relevance Heat
Disorders Of Creatine Metabolism 64 100.00 Very High Very High Very High
Apoptosis 7 99.92 Very High Very High Very High
Nicotine Addiction 44 99.84 Very High Very High Very High
INFLAMMATION 25 99.40 Very High Very High Very High
Hypertension 26 96.16 Very High Very High Very High
Diabetes Mellitus 71 95.60 Very High Very High Very High
Manic Depressive Disorder 1 94.48 High High
Nephrotoxicity 12 94.40 High High
Obesity 18 94.32 High High
Overactive Bladder 1 93.52 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Association of levels of N-acetyl-beta-glucosaminidase with specific psychiatric symptoms in bipolar patients.
N-acetyl-beta-glucosaminidase Binding (Association) of
1) Confidence 0.34 Published 1993 Journal Psychiatry Res Section Title Doc Link 8341766 Disease Relevance 0.50 Pain Relevance 0.15
As shown in Figure 2A, the cutoff concentrations of NAG and protein HC obtained by our hybrid
NAG Binding (obtained) of
2) Confidence 0.31 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1513341 Disease Relevance 0 Pain Relevance 0
GFR; NAG and protein HC displayed no such associations.
NAG Neg (no) Binding (associations) of
3) Confidence 0.31 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1513341 Disease Relevance 0.19 Pain Relevance 0.09
The following thrombo-inflammatory markers were measured at all timepoints: Plasma IL-6, HsCRP, TAT complex, Fibrin D-dimer, urinary protein, albumin and NAG.
NAG Binding (timepoints) of in Plasma associated with inflammatory marker
4) Confidence 0.23 Published 2006 Journal Thromb J Section Body Doc Link PMC1540420 Disease Relevance 0.25 Pain Relevance 0.05
Finally, in the oldest tertile of workers, associations between lead dose and NAG were unchanged, but fewer associations between the lead biomarkers and the clinical renal outcomes remained significant (p ?
NAG Binding (associations) of
5) Confidence 0.18 Published 2005 Journal Environ Health Perspect Section Abstract Doc Link PMC1253707 Disease Relevance 0.07 Pain Relevance 0.04
Associations between lead dose and NAG were unchanged, and uric acid was inversely associated with RBP.
NAG Binding (Associations) of
6) Confidence 0.18 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1253707 Disease Relevance 0.24 Pain Relevance 0
As shown in Table 6, associations between the lead measures and NAG were unchanged after adjustment for uric acid.
NAG Binding (associations) of
7) Confidence 0.17 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1253707 Disease Relevance 0 Pain Relevance 0
In never-smokers, cadmium remained associated with protein HC and NAG and became significantly associated with creatinine clearance (blood cadmium).
NAG Binding (associated) of in blood associated with nicotine addiction and disorders of creatine metabolism
8) Confidence 0.10 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1310929 Disease Relevance 1.27 Pain Relevance 0.09
Cadmium in urine was significantly associated with GFR, creatinine clearance, protein HC, and NAG, after controlling for confounders and adjusting for other covariables (Table 3).
NAG Binding (associated) of in urine associated with disorders of creatine metabolism
9) Confidence 0.10 Published 2005 Journal Environ Health Perspect Section Body Doc Link PMC1310929 Disease Relevance 1.17 Pain Relevance 0.10
Intersex toads had plasma testosterone concentrations that were similar to NAgFs and were not different from BidderÂ’s males and AgMs, but were significantly lower than NAgMs.
NAgMs Binding (lower) of in plasma
10) Confidence 0.04 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2592273 Disease Relevance 0.12 Pain Relevance 0
Pretreatment with the antioxidant N-acetyl-L-cystein and catalase, but not superoxide dismutase, completely inhibited capsaicin-induced apoptosis by inhibiting phosphorylation of Ser-15 residue of p53.
N-acetyl-L-cystein Neg (not) Binding (Pretreatment) of associated with qutenza and apoptosis
11) Confidence 0.02 Published 2004 Journal Cancer Res. Section Abstract Doc Link 14871840 Disease Relevance 0.65 Pain Relevance 1.11

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