INT58994

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Context Info
Confidence 0.79
First Reported 1993
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 3.37
Pain Relevance 1.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mcpt2) intracellular (Mcpt2)
Anatomy Link Frequency
mast cell 6
Small intestine 1
Mcpt2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 20 92.80 High High
Inflammation 6 90.40 High High
nud 6 89.60 High High
spastic colon 3 89.20 High High
antagonist 1 87.92 High High
tetrodotoxin 1 80.32 Quite High
Pain threshold 1 78.24 Quite High
Serotonin 1 69.68 Quite High
cytokine 1 56.84 Quite High
qutenza 4 33.12 Quite Low
Disease Link Frequency Relevance Heat
Hypersensitivity 9 97.80 Very High Very High Very High
Urological Neuroanatomy 2 97.72 Very High Very High Very High
Bordatella Infection 3 97.12 Very High Very High Very High
Injury 1 96.64 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

2 96.08 Very High Very High Very High
Functional Bowel Disorder 6 90.96 High High
Dyspepsia 6 89.60 High High
INFLAMMATION 4 86.48 High High
Sprains And Strains 3 86.08 High High
Food Hypersensitivity 3 85.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Rat mast cell protease II (RMCP II) release in response to OVA challenge and immunoglobulin E (IgE) concentration were measured in serum.
Localization (release) of RMCP II in mast cell
1) Confidence 0.79 Published 2005 Journal Neurogastroenterol. Motil. Section Abstract Doc Link 15670271 Disease Relevance 0.63 Pain Relevance 0.09
We recently demonstrated that peptones, such as ovalbumin hydrolysate (OVH), induce the release of rat mast cell protease II (RMCP II), indicating IMMC degranulation.
Localization (release) of RMCP II in IMMC
2) Confidence 0.79 Published 2003 Journal Regul. Pept. Section Abstract Doc Link 12609751 Disease Relevance 0.16 Pain Relevance 0.24
Rat mast cell protease II (RMCP II) release in response to OVA challenge and immunoglobulin E (IgE) concentration were measured in serum.
Localization (release) of mast cell protease II in mast cell
3) Confidence 0.69 Published 2005 Journal Neurogastroenterol. Motil. Section Abstract Doc Link 15670271 Disease Relevance 0.64 Pain Relevance 0.09
We recently demonstrated that peptones, such as ovalbumin hydrolysate (OVH), induce the release of rat mast cell protease II (RMCP II), indicating IMMC degranulation.
Localization (release) of mast cell protease II in IMMC
4) Confidence 0.68 Published 2003 Journal Regul. Pept. Section Abstract Doc Link 12609751 Disease Relevance 0.16 Pain Relevance 0.24
This hypothesis was confirmed by inhibition of antigen-induced release of the specific mucosal mast cell marker, rat mast cell protease II, in tissues treated with IFN alpha/beta.
Localization (release) of mast cell protease II in mast cell
5) Confidence 0.67 Published 1993 Journal Reg Immunol Section Abstract Doc Link 8347470 Disease Relevance 0 Pain Relevance 0.23
Small intestine sections from orally sensitized rats released more RMCP II than sections from control rats.
Localization (released) of RMCP II in Small intestine
6) Confidence 0.61 Published 2005 Journal Neurogastroenterol. Motil. Section Abstract Doc Link 15670271 Disease Relevance 0.70 Pain Relevance 0.06
In an organ culture, spontaneous release of a mucosal mast cell-specific protease (RMCP-2) from the distal colon tissue of TNBS-treated rats was significantly larger than that of sham animals.
Localization (release) of RMCP-2 in mast cell
7) Confidence 0.55 Published 2007 Journal J. Vet. Med. Sci. Section Abstract Doc Link 18176016 Disease Relevance 0.91 Pain Relevance 0.34

General Comments

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