INT59010

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Context Info
Confidence 0.27
First Reported 1993
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 2.11
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Crp) extracellular region (Crp)
Anatomy Link Frequency
joint 2
Crp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 1 100.00 Very High Very High Very High
methotrexate 11 99.84 Very High Very High Very High
Inflammation 48 99.64 Very High Very High Very High
alcohol 1 98.24 Very High Very High Very High
antagonist 6 90.72 High High
Earache 1 76.32 Quite High
abdominal pain 2 74.60 Quite High
Angina 23 69.20 Quite High
cva 2 68.48 Quite High
ischemia 1 49.04 Quite Low
Disease Link Frequency Relevance Heat
Pain 1 100.00 Very High Very High Very High
INFLAMMATION 54 99.64 Very High Very High Very High
Acute Coronary Syndrome 32 99.48 Very High Very High Very High
Rheumatoid Arthritis 1 97.24 Very High Very High Very High
Granuloma 1 96.72 Very High Very High Very High
Otitis Media 1 85.80 High High
Hemoptysis 3 79.52 Quite High
Earache 1 76.32 Quite High
Respiratory Failure 1 75.20 Quite High
Abdominal Pain 2 74.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
MTX (5 mg) induced a significant effect on the Ritchie joint index, morning stiffness, pain, ESR and C-reactive protein.
Positive_regulation (induced) of Regulation (effect) of C-reactive protein in joint associated with pain and methotrexate
1) Confidence 0.27 Published 1993 Journal Br. J. Rheumatol. Section Abstract Doc Link 8348281 Disease Relevance 0.20 Pain Relevance 0.51
We sought to identify whether pro-inflammatory genetic variants contributed to alterations in WBC and C-reactive protein (CRP) in an ACS population.


Spec (whether) Positive_regulation (contributed) of Spec (whether) Regulation (alterations) of C-reactive protein associated with acute coronary syndrome and inflammation
2) Confidence 0.05 Published 2004 Journal BMC Med Genet Section Abstract Doc Link PMC425582 Disease Relevance 0.93 Pain Relevance 0.29
Analytical tests showed increased values of C-reactive protein and the presence of high-titer anti-PR3 antibodies.
Positive_regulation (increased) of Regulation (values) of C-reactive protein
3) Confidence 0.01 Published 2009 Journal The Open Respiratory Medicine Journal Section Body Doc Link PMC2705845 Disease Relevance 0.98 Pain Relevance 0.29

General Comments

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