INT59167

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Context Info
Confidence 0.35
First Reported 1993
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 9
Disease Relevance 7.33
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CSRP1)
Anatomy Link Frequency
blood 1
heart 1
CSRP1 (Homo sapiens)
CSRP1 - S181G (3)
Pain Link Frequency Relevance Heat
abdominal pain 23 97.64 Very High Very High Very High
Pain 10 84.72 Quite High
rheumatoid arthritis 1 75.00 Quite High
Chronic pancreatitis 16 74.28 Quite High
fibrosis 4 74.12 Quite High
nud 6 43.08 Quite Low
Angina 1 36.24 Quite Low
imagery 11 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 97 100.00 Very High Very High Very High
Thrombocytopenia 1 100.00 Very High Very High Very High
Proteinuria 1 100.00 Very High Very High Very High
Pancreatitis 115 99.76 Very High Very High Very High
Acute Renal Failure 1 99.20 Very High Very High Very High
Coronary Artery Disease 8 99.08 Very High Very High Very High
Hantavirus Infection 5 98.88 Very High Very High Very High
Pulmonary Disease 93 98.84 Very High Very High Very High
Hemorrhage 1 98.24 Very High Very High Very High
Abdominal Pain 23 97.64 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A combination of thrombocytopenia, proteinuria, elevated CrP and creatinin is common in hemorrhagic fever with renal syndrome (HFRS) due to Hantavirus infection.
CrP Binding (combination) of associated with proteinuria, thrombocytopenia and hantavirus infection
1) Confidence 0.35 Published 2008 Journal Praxis Section Abstract Doc Link 18548800 Disease Relevance 1.70 Pain Relevance 0.17
Sociodemographic variables were overall more frequently and strongly associated with CWP than with CRP, which indicates different pathophysiology in the development or preservation of pain in the 2 groups.


CRP Binding (associated) of
2) Confidence 0.11 Published 2001 Journal J. Rheumatol. Section Body Doc Link 11409133 Disease Relevance 0 Pain Relevance 0
CRP was also associated with being a manual worker (OR 1.63, 95% CI 1.19-2.23) vs being an intermediate/higher nonmanual employee.
CRP Binding (associated) of
3) Confidence 0.11 Published 2001 Journal J. Rheumatol. Section Body Doc Link 11409133 Disease Relevance 0 Pain Relevance 0
Man et al took this one step further and demonstrated that ratios of blood biomarkers, in this case fibronectin and CRP, are significantly associated with all-cause mortality of COPD patients [52].
CRP Binding (associated) of in blood associated with pulmonary disease
4) Confidence 0.10 Published 2009 Journal Respir Res Section Body Doc Link PMC2678087 Disease Relevance 1.29 Pain Relevance 0.11
On admission patients were diagnosed with coronary heart disease based on laboratory markers specific for the disease (CK, troponin, LDH,CRP), ECG and history taking.
CRP Binding (disease) of in heart associated with coronary artery disease and disease
5) Confidence 0.05 Published 2008 Journal Coll Antropol Section Abstract Doc Link 18756883 Disease Relevance 1.25 Pain Relevance 0
Multiple regression with PJC, MS and RC as dependent variables showed significant associations of PJC with PV, MS and CRP and RC with PV.
CRP Binding (associations) of
6) Confidence 0.05 Published 1993 Journal Br. J. Rheumatol. Section Abstract Doc Link 8369887 Disease Relevance 0.91 Pain Relevance 0.12
In the present report, the combined genotype F508del/S181G is associated with acute pancreatitis episodes in the 6-year-old proband, but not in his 37-year-old mother, who carries the same genotype, but without any pancreatic symptoms, biochemical or ultrasound pancreatic alterations.
S181G (S181G) Binding (associated) of associated with pancreatitis
7) Confidence 0.01 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2970583 Disease Relevance 0.60 Pain Relevance 0.07
At the pre</span>sent knowledge it can be only stated that the combined genotype CFTR (F508del)/PRSS1 (S181G) is associated to a mild phenotype of acute recurrent pancreatitis in this child without any further conclusion on its pathogenetic role or prediction on the course of the disease.



S181G (S181G) Binding (associated) of associated with pancreatitis and disease
8) Confidence 0.01 Published 2010 Journal BMC Gastroenterol Section Abstract Doc Link PMC2970583 Disease Relevance 0.75 Pain Relevance 0.07
At the moment, the combined genotype F508del/S181G could be only associated to a mild phenotype of acute recurrent pancreatitis as happened in the present child.
S181G (S181G) Binding (associated) of associated with pancreatitis
9) Confidence 0.01 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2970583 Disease Relevance 0.82 Pain Relevance 0

General Comments

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