INT59286

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.62
First Reported 1993
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 7
Total Number 8
Disease Relevance 6.13
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (EPO) extracellular space (EPO) aging (EPO)
extracellular region (EPO)
Anatomy Link Frequency
blood 2
EPO (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 11 69.60 Quite High
cytokine 8 60.40 Quite High
addiction 2 54.08 Quite High
rheumatoid arthritis 2 47.52 Quite Low
Pain 4 43.12 Quite Low
vincristine 1 36.56 Quite Low
cva 8 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anaemia 176 99.72 Very High Very High Very High
Hypoxia 97 97.84 Very High Very High Very High
Renal Disease 8 97.68 Very High Very High Very High
Pulmonary Disease 1 96.12 Very High Very High Very High
Myelodysplastic Syndromes 41 95.80 Very High Very High Very High
Apnoea 1 95.24 Very High Very High Very High
Nicotine Addiction 2 93.72 High High
Erythrocytosis 17 92.24 High High
Chronic Renal Failure 25 91.84 High High
Oxyphilic Adenoma 7 89.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We review data concerning site and regulation of erythropoietin (EPO) production, its effects on target tissue, routes of administration and clinical applications.
Regulation (regulation) of Gene_expression (production) of erythropoietin
1) Confidence 0.62 Published 1993 Journal Neth J Med Section Abstract Doc Link 8377877 Disease Relevance 0.84 Pain Relevance 0.03
The Epo response depends on the hypoxia signal, not on the absolute number of erythrocytes in the blood, and therefore compensating mechanisms may modify the Epo expression.
Spec (may) Regulation (modify) of Gene_expression (expression) of Epo in blood associated with hypoxia
2) Confidence 0.49 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504072 Disease Relevance 1.13 Pain Relevance 0
We review data concerning site and regulation of erythropoietin (EPO) production, its effects on target tissue, routes of administration and clinical applications.
Regulation (regulation) of Gene_expression (production) of EPO
3) Confidence 0.45 Published 1993 Journal Neth J Med Section Abstract Doc Link 8377877 Disease Relevance 0.84 Pain Relevance 0.03
The serum erythropoietin levels were within the normal range in this case and dropped by 17% one year after the operation, in parallel with stabilisation of the hematocrit to normal levels.
Regulation (dropped) of Gene_expression (levels) of erythropoietin
4) Confidence 0.43 Published 2006 Journal BMC Urol Section Body Doc Link PMC1590043 Disease Relevance 1.85 Pain Relevance 0
There is emerging evidence to suggest that the adverse effects of anemia are not only related to Hb levels but also to the low levels of EPO.
Regulation (related) of Gene_expression (levels) of EPO associated with anaemia
5) Confidence 0.43 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2673829 Disease Relevance 1.12 Pain Relevance 0.03
Two weeks prior to rhEpo treatment all subjects received 100 mg iron.day?
Regulation (subjects) of Gene_expression (treatment) of rhEpo
6) Confidence 0.39 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2500186 Disease Relevance 0 Pain Relevance 0
These prognostic factors included eEPO concentrations ?
Regulation (included) of Gene_expression (concentrations) of eEPO
7) Confidence 0.24 Published 2008 Journal British Journal of Haematology Section Body Doc Link PMC2654479 Disease Relevance 0.34 Pain Relevance 0.03
Surprisingly using non linear correlations the most important variable influencing the epoetin requirement expressed in units/kg/week is the weight.
Regulation (influencing) of Gene_expression (expressed) of epoetin
8) Confidence 0.20 Published 2006 Journal BMC Nephrol Section Body Doc Link PMC1578551 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox