INT59386

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Context Info
Confidence 0.06
First Reported 1993
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.41
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tgfa) extracellular region (Tgfa) plasma membrane (Tgfa)
nucleus (Tgfa)
Anatomy Link Frequency
fibroblast 1
Tgfa (Mus musculus)
Pain Link Frequency Relevance Heat
tetrodotoxin 2 98.52 Very High Very High Very High
Action potential 3 98.24 Very High Very High Very High
sodium channel 1 94.00 High High
cytokine 5 87.56 High High
Potency 1 41.68 Quite Low
metalloproteinase 1 14.28 Low Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 70 77.68 Quite High
Solid Tumor 8 70.84 Quite High
Cancer 29 39.60 Quite Low
Exanthema 31 5.00 Very Low Very Low Very Low
Toxicity 23 5.00 Very Low Very Low Very Low
Non-small-cell Lung Cancer 17 5.00 Very Low Very Low Very Low
Disease 16 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 9 5.00 Very Low Very Low Very Low
Colon Cancer 5 5.00 Very Low Very Low Very Low
Interstitial Lung Diseases 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The extracellular ligand-binding domain binds specific ligands including EGF, transforming growth factor alpha (TGF?)
transforming growth factor alpha Binding (ligands) of
1) Confidence 0.06 Published 2008 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2727779 Disease Relevance 0.41 Pain Relevance 0
By contrast, for expression of more mature action potentials (tetrodotoxin-sensitive) one of the interleukins IL-5, IL-7 or IL-9 must be applied in association with transforming growth factor-alpha after pretreatment with basic fibroblast growth factor.
growth factor-alpha Binding (association) of in fibroblast associated with tetrodotoxin and action potential
2) Confidence 0.02 Published 1993 Journal Nature Section Abstract Doc Link 8383296 Disease Relevance 0 Pain Relevance 0.52

General Comments

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