INT59387

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Context Info
Confidence 0.36
First Reported 1993
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.91
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il9) extracellular region (Il9)
Anatomy Link Frequency
fibroblast 1
mast cells 1
Il9 (Mus musculus)
Pain Link Frequency Relevance Heat
tetrodotoxin 2 99.00 Very High Very High Very High
Action potential 3 98.72 Very High Very High Very High
sodium channel 1 94.96 High High
cytokine 54 88.52 High High
chemokine 8 81.96 Quite High
Inflammation 31 57.20 Quite High
fibrosis 3 5.00 Very Low Very Low Very Low
tolerance 3 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 8 99.20 Very High Very High Very High
Airway Remodeling 10 90.20 High High
Schistosomiasis 1 82.40 Quite High
Asthma 117 79.60 Quite High
Mastocytosis 1 76.40 Quite High
Apoptosis 1 71.20 Quite High
INFLAMMATION 32 57.20 Quite High
Hypersensitivity 25 56.40 Quite High
Sprains And Strains 5 48.96 Quite Low
Hyperplasia 4 43.52 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The potential for IL-9 to be a mast cell growth factor has been recognized in studies of IL-9 transgenic mice which have significantly increased levels of mast cells in various tissues including the lung (Godfraind et al. 2009; Temann et al. 1988).
IL-9 Binding (recognized) of in mast cells associated with targeted disruption
1) Confidence 0.36 Published 2010 Journal Immunogenetics Section Body Doc Link PMC2910299 Disease Relevance 0.66 Pain Relevance 0.03
Nicolaides and colleagues were the first to show a close association between the IL-9 gene and bronchial hyperresponsiveness [48].
IL-9 gene Binding (association) of
2) Confidence 0.12 Published 2010 Journal Journal of Allergy Section Body Doc Link PMC2957587 Disease Relevance 0.25 Pain Relevance 0.08
By contrast, for expression of more mature action potentials (tetrodotoxin-sensitive) one of the interleukins IL-5, IL-7 or IL-9 must be applied in association with transforming growth factor-alpha after pretreatment with basic fibroblast growth factor.
IL-9 Binding (association) of in fibroblast associated with tetrodotoxin and action potential
3) Confidence 0.11 Published 1993 Journal Nature Section Abstract Doc Link 8383296 Disease Relevance 0 Pain Relevance 0.53

General Comments

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