INT59530

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Context Info
Confidence 0.49
First Reported 1993
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.18
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (REG1A)
Anatomy Link Frequency
pancreas 2
spinal cord 2
REG1A (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 2 98.12 Very High Very High Very High
Action potential 16 97.84 Very High Very High Very High
anesthesia 1 95.36 Very High Very High Very High
depression 90 78.56 Quite High
c fibre 1 77.32 Quite High
Dorsal horn 4 76.32 Quite High
long-term potentiation 80 49.28 Quite Low
primary afferent fibers 1 25.00 Low Low
primary somatosensory cortex 12 5.00 Very Low Very Low Very Low
Hippocampus 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 1 99.64 Very High Very High Very High
Stress 1 96.48 Very High Very High Very High
Depression 92 78.56 Quite High
Sepsis 1 75.00 Quite High
Li-fraumeni Syndrome 98 71.60 Quite High
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low
Anaerobic Bacterial Infections 2 5.00 Very Low Very Low Very Low
Nervous System Injury 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
OBJECTIVES: The level of pancreatic stone protein/regenerating protein (PSP/reg), a secretory protein produced in the pancreas, increases dramatically during pancreatic disease.
Positive_regulation (increases) of Gene_expression (produced) of reg in pancreas associated with pancreatitis
1) Confidence 0.49 Published 2009 Journal Crit. Care Med. Section Abstract Doc Link 19325491 Disease Relevance 0.27 Pain Relevance 0.10
These results indicate that, although the generation of long-lasting "slow" PSPs by high-threshold primary afferents is necessary for the summation of synaptic activity in the spinal cord at low frequencies, the rate and pattern of the summation does not depend on the absolute duration of the PSPs.
Positive_regulation (necessary) of Gene_expression (generation) of PSPs in spinal cord associated with spinal cord
2) Confidence 0.34 Published 1993 Journal J. Neurophysiol. Section Abstract Doc Link 8389833 Disease Relevance 0 Pain Relevance 0.41
For all experiments (except when noted) PSPs were evoked by alternate stimulation of both horizontal pathways at 0.1?
Positive_regulation (experiments) of Gene_expression (evoked) of PSPs
3) Confidence 0.06 Published 2009 Journal Neural Plasticity Section Body Doc Link PMC2832108 Disease Relevance 0.45 Pain Relevance 0.15
For all experiments (except when noted) PSPs were evoked by alternate stimulation of both horizontal pathways at 0.1?
Positive_regulation (stimulation) of Gene_expression (evoked) of PSPs
4) Confidence 0.06 Published 2009 Journal Neural Plasticity Section Body Doc Link PMC2832108 Disease Relevance 0.46 Pain Relevance 0.15

General Comments

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